Monday 29 July 2019

Dermatophytic Onychomycosis Treatment Market Growth Rate Analysis 2026


Dermatophytic onychomycosis, also known as tinea unguium, is a fungal disease of toenails or fingernails that causes ring infection over nails. Trichophyton rubrum and trichophyton mentagrophytes are common strains of fungi responsible for causing dermatophytic onychomycosis. Furthermore, yeasts and non-dermatophyte molds are other agents that spread the infection. Public places such as gym, swimming pool, and others that are infected with disease causing fungal agents are major source, which cause dermatophytic onychomycosis. Moreover, continuous use of shoes for a longer duration and contact of toe nail with wet surface causes the fungal infection. Increasing incidences of the infection are evident in sportsperson, owing to continuous use of shoe, sweating at nails, and traumatic nail injuries.


Major symptoms of dermatophytic onychomycosis include thickening and whitening of nails. Moreover, the nails become brittle and appear white as the infection progresses. People suffering from diabetes, peripheral vascular disease, HIV, immune suppression, obesity, and geriatric population are at increased risk of this common fungal infection. Dermatophytic onychomycosis could be treated with either topical preparations or oral antifungal agents based on the severity of infection. The treatment often lasts for an average period of six months. In recent past, advancement in therapy with the introduction of effective topical and oral products has controlled the rapid spread of dermatophytic onychomycosis.

The global dermatophytic onychomycosis treatment market size was valued at US$ 2,596.8 million in 2017, and is expected to witness a CAGR of 12.6% over the forecast period (2018 – 2026).

Increased global prevalence of dermatophytic onychomycosis is expected to propel growth of the dermatophytic onychomycosis treatment market

Dermatophytic onychomycosis is most common nail disorder. According to a report in the Journal of Cutaneous Medicine and Surgery, 2017, onychomycosis accounts for 50% of all nail diseases and prevalence of onychomycosis was estimated to be 5.5% with margin of error of + 3% worldwide. Prophylactic use of topical antifungal agent is expected to aid in effective treatment of dermatophytic onychomycosis, which in turn is major factor contributing to the market growth.

Development of new therapies that aid in treatment of dermatophytic onychomycosis is expected to drive growth of the dermatophytic onychomycosis treatment market over the forecast period

Introduction of new drug candidates and adoption of new treatment approaches is a major factor contributing to the dermatophytic onychomycosis treatment market growth. For instance, in 2014, the U.S. Food and Drug Administration (FDA) approved two new topical antifungal drugs—efinaconazole and tavaborole— for the treatment of dermatophytic onychomycosis caused by Trichophyton rubrum and Trichophyton mentagrophytes. Efinaconazole is the first approved topical triazole antifungal agent and tavaborole is the first approved oxobarole antifungal agent for this indication. These agents offer short treatment courses, high cure rates, and few relapse cases.

Key players operating in the dermatophytic onychomycosis treatment market include, Bausch Health Companies, Galderma S.A., Celtic Pharma, Anacor pharmaceuticals, Inc., Johnson & Johnson, Novartis AG, Pfizer Inc., GlaxoSmithKline, Topica Pharmaceuticals, Inc., Moberg Pharma AB, Bayer AG, Dr. Reddy’s Laboratories Ltd, Allergen, Inc., Cipla Ltd, Medimetriks Pharmaceuticals Inc., Sanofi S.A., NovaBiotics Inc., and Merz Pharma.

Detailed Segmentation:

Global Dermatophytic Onychomycosis Treatment Market, By Therapy Type:
  • Systemic Therapy
  • Topical Therapy
  • Device-based Therapy

Global Dermatophytic Onychomycosis Treatment Market, By End User:
  • Hospitals
  • Dermatology Clinics
  • Retail Pharmacies
  • Others

Global Dermatophytic Onychomycosis Treatment Market, By Geography:
  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa


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Friday 26 July 2019

Tylosin Market: Checkout the Unexpected Future Growth


Tylosin is used in livestock for various purposes such as a feed additive for growth promotion and as an antibiotic against infectious diseases in animals such as chickens, turkeys, felines, canines, pigs, calves, and others. These antibiotics aid in the treatment of chronic respiratory disease (CRD) associated with Mycoplasma Gallisepticum and Mycolplasma synoviae and other infections.

Tylosin is used for treatment and control of swine dysentery associated with Brachyspira Hyodysenteriae and for the control of porcine proliferate enteropathies in pigs. Moreover, Tylosin is highly effective in tylosin-responsive diarrhea in dogs, which is a canine chronic, recurrent diarrhea that responds repeatedly to Tylosin treatment.


Market Dynamics

The global Tylosin market is expected to witness significant growth over the forecast period, owing to rising demand for Tylosin in livestock industry. For instance, according to a study by Ministry for Primary Industries, New Zealand 2016, Tylosin accounted for over 83% of macrolide and lincosamide sales during 2011 and 2014 and the trend is expected to continue over the forecast period.

Moreover, certain mergers and acquisitions are expected to boost the market growth over the forecast period. For instance, Eily, Lilly, and Company acquired Novartis Animal Health in 2014. Varied product offering by manufacturers such as Elanco Animal Health is expected to propel the global Tylosin market growth over the forecast period. For instance, Elanco offers Component with Tylan, an implant line with initial and terminal implants for steers and heifers. This implant includes a tylosin tartrate (Tylan) pellet that dissolves and releases antibacterial throughout the implant site.

The global Tylosin market size was valued at US$ 379.0 million in 2017, and is expected to witness a CAGR of 1.2% over the forecast period (2018 – 2026).

Increasing demand for healthy livestock is expected to support growth of global Tylosin market over the forecast period

The demand for livestock animals for consumption is on the rise worldwide and is expected to maintain the positive growth in demand over the forecast period. Subsequently, the demand for infection-free and healthy livestock used primarily for consumption is increasing. However, the prevalence of various microbial infections is high in both humans and animals. For instance, according to the Centers for Disease Control and Prevention (CDC), 2017, zoonotic diseases are common in the U.S. and worldwide and over 6 out of every 10 known infectious diseases in humans are spread from animals. Hence, antibiotics are an important medication for livestock that aide in providing healthy food products for consumption in humans.

Key players operating in the global Tylosin market include Zoetis, Tairui Pharmaceuticals, Lukang Pharmaceutical, Henan Hualun, Qilu Pharmaceutical (Inner Mongolia) Co., Ltd, Huvepharma, AdvaCare Pharma, and Elanco Animal Health.

Detailed Segmentation:

Global Tylosin Market, By Drug Type:
  • Tylosin Phosphate
  • Tylosin Tartrate
  • Others
Global Tylosin Market, By Application:
  • Felines
  • Canines
  • Livestock
  • Others
Global Tylosin Market, By Route Of Administration:
  • Oral
  • Injectable


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Hormone Replacement Therapy Market Anticipates Steady Growth Till 2026


New mergers and acquisitions is one of the major factor driving the growth of the hormone replacement therapy market. For instance, in 2014, Pfizer Inc., a U.S.-based pharmaceutical company, merged with OPKO Health Inc., a U.S.-based company, to develop a long acting growth hormone (hGH-CTP) and innovative treatments for growth hormone deficient patients. hGH-CTP is more convenient, as the patients need to take just one injection in a week rather than daily doses. hGH-CTP has an orphan drug designation in the U.S. and Europe for adults and children with growth hormone deficiency.

Robust pipeline is also expected to support growth of the hormone replacement therapy market size. For instance, Somapacitan sponsored by Novo Nordisk A/S, a Denmark-based company, completed phase 3 clinical trials in 2017. This drug is used for the treatment of growth hormone deficiency in adults.

The global hormone replacement therapy market size was valued at US$ 10.58 billion in 2017 and is expected to witness a CAGR of 5.2% over the forecast period (2018 – 2026).


Increasing prevalence of various chronic conditions are expected to drive growth of the hormone replacement therapy market

Increasing prevalence of hypogonadism in adult men worldwide is expected to drive growth of the hormone replacement therapy market. According to the European Association of Urology: 2016 report, in middle-aged men, the incidence of hypogonadism varies from 2.1% to 12.8%. The incidence of low testosterone and symptoms of hypogonadism in men aged 40-79 varies form 2.1% to 5.7%, in Europe. Ease in access and government support for research and development activities is expected to aid in growth of the hormone replacement therapy market. Financial help by NGOs such as the National Gaucher Society help patients receive enzyme replacement therapy that are costly.

Hormone Replacement Therapy Market - Regional Insights

On the basis of region, the global hormone replacement therapy market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold dominant position in the global hormone replacement therapy market, owing to continuous launch of various generic products for hormone replacement therapies by manufacturers. Furthermore, Europe is expected to be the second largest contributor to the hormone replacement therapy market, in terms of revenue and is expected to gain significant traction in the near future. This is owing to launch of new drugs and therapies to combat secondary hyperparathyroidism and presence of significant population suffering from the disease in this region. For instance, in December 2016, Amgen’s drug etecalcetide (Parsabiv) received marketing approval in Europe by the European Commission for the treatment of secondary hyperparathyroidism in adult patients with chronic kidney diseases.

Hormone Replacement Therapy Market - Competitive Landscape

Manufacturers are focusing on developing generic versions of various drugs for the treatment of certain disorders that are highly prevalent in women such as hypothyroidism. For instance, Teva Pharmaceutical Industries Ltd. launched generic version of Vagifem (estradiol vaginal inserts), 10 mcg in the U.S. on 24, July 2017. Estradiol vaginal inserts are an estrogen indicated for the treatment of atrophic vaginitis due to menopause.

Key players operating in the global hormone replacement therapy market include Novartis AG, Abbott Laboratories, Mylan N.V., Merck KgaA, Bayer AG, Pfizer Inc., Novo Nordisk A/S, QuatRx Pharmaceuticals, Teva Pharmaceutical Industries Ltd., Amgen, Inc., and Eli Lilly and Company.

Detailed Segmentation:

Global Hormone Replacement Therapy Market, By Therapy Type:
  • Estrogen Replacement Therapy
  • Human Growth Hormone (HGH) Replacement Therapy
  • Thyroid Replacement Therapy
  • Testosterone Replacement Therapy

Global Hormone Replacement Therapy Market, By Route of Administration:
  • Oral
  • Parenteral
  • Others

Global Hormone Replacement Therapy Market, By Application:
  • Hypothyroidism
  • Male Hypogonadism
  • Growth Hormone Deficiency
  • Menopause
  • Others


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Monday 22 July 2019

Ranitidine Market – Global Industry Insights to 2026


Healthcare professionals have been keenly interested in the treatment of gastroesophageal reflux disease (GERD) and stomach & intestinal ulcer owing to its increasing prevalence. GERD is common health problem, which leads to serious medical complications and further huge medical expense in its diagnosis and treatment. The two most frequently observed symptoms associated with GERD are heartburn and acid regurgitation. Usually, over-the-counter antacids, proton pump inhibitor, and H-2 receptor blockers are used to decrease the effects of stomach acids or to block acid production.

Ranitidine is a histamine H2 antagonists and available as both over-the-counter (OTC) and prescription drug, indicated in the treatment of gastroesophageal reflux disease (GERD). Ranitidine decreases the acid production from stomach for up to 12 hours. Also, ranitidine is commonly used in erosive esophagitis, peptide ulcer disease, and Zollinger–Ellison syndrome. It could be taken orally or intravenously.


The global ranitidine market size was valued at US$ 412.4 Mn in 2017, and is expected to witness a CAGR of 1.8% over the forecast period (2018 – 2026).

Growing Research and Development (R&D) on Ranitidine is expected to Boost Market Growth

Various government and private research organizations are increasingly engaged in research and development studies to increase the efficacy of ranitidine and examine possible potential of ranitidine to increase future scope of ranitidine market.

Furthermore, various clinical trials are currently undergoing to identify and compare efficacy between ranitidine and other proton pump inhibitors such as esomeprazole and rabeprazole to measure gastric acid reduction in stomach. With the result of these studies, the efficacy of ranitidine is expected to improve and offer better treatment regimes in reducing excessive gastric acid production in the near future.

Rising Cases of Various Gastric Ulcers and Digestive Diseases is expected to Increase Growth of the market

High prevalence of gastroesophageal reflux disease (GERD), intestinal & stomach ulcers, esophagitis, heartburn, and other digestive diseases due to unhealthy lifestyle, changing dietary patterns will lead to increase in demand for ranitidine-based medications in the near future. According to Florida Hospital, 2018 U.S. data statistics, in the U.S. over 60 million adults suffer from acid reflux symptoms every month. Furthermore, the source states that each day an estimated 25 million of the 60 million adults suffers from acid reflux symptoms. Also, according to the same source, about 20% of people with acid reflux will develop gastroesophageal reflux disease (GERD) in the near future.

Heartburn with or without regurgitation is identified as one of the prime symptoms of gastroesophageal reflux disease (GERD). According to World Gastroenterology Organization (WGO), 2015, prevalence of GERD is rapidly increasing worldwide, with differences reported in prevalence ranging from 2.5% to 6.6% in Eastern Asia while slightly higher up to 13.8% to 25.8% in North America.


Key players operating in the global ranitidine market include GlaxoSmithKline plc, Boehringer Ingelheim GmbH, Strides Pharma Science Limited (StridesShasun), Tocris Bioscience (R & D Systems), Merck KGaA, and Sun Pharmaceutical Industries Limited among others.

Detailed Segmentation:

Global Ranitidine Market, By Strength:
  • 75 mg
  • 150 mg
  • 300 mg

Global Ranitidine Market, By Form:
  • Tablet
  • Syrup
  • Injection

Global Ranitidine Market, By Route of Administration:
  • Oral
  • Intravenous
  • Global Ranitidine Market, By Application:
  • Intestinal & Stomach Ulcers
  • Gastroesophageal Reflux Disease (GERD)
  • Esophagitis
  • Zollinger-Ellison Syndrome
  • Other Application

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Thursday 18 July 2019

Medical Implants Sterile Packaging Market 2017 | Industry Growth, Size, Outlook, 2025

Thermoform Engineered Quality has developed a new solution—TEQpropylene that is intended to reduce sterile packaging costs and harmful environmental impacts. The strength, sustainability, and clarity improvements of TEQpropylene offers cost-effective packaging. Moreover, pouches made by Tyvek are used for packaging various sterilized medical devices, particularly those devices that are low profile and light weight. Sterilization pouches made by Tyvek are used in outpatient surgical centers and in house sterilization of surgical instruments, owing to its resistance to microbial penetration. Such resistance aid in retaining sterility of contents in pouches until opened. Moreover, Tyvek pouches provide superior puncture resistance and tear strength as compared to medical-grade papers, which is a major factor contributing to increase in demand for its use in sterilization of medical devices.
The global medical implants sterile packaging industry over the last few decades have observed a notable growth due to significant increase in the number of implant products. Medical implants sterile packaging has been widely used in the packaging of joint, spinal, and support implants, owing to anti contaminant and high-performance factors. Sterile packaging plays a vital role in the life-saving pharmaceuticals drugs and medical devices.
However, there are other implants, which deliver medication, provide support to tissues and organs, and monitor body functions. Clamshell pack is one of the fastest growing segments in the medical implants sterile packaging market. Clamshell packaging has numerous advantages with respect to appearance, portability, and convenience. It is mainly used to pack various medical and surgical appliances and instruments.
According to American Association of Oral and Maxillofacial Surgeons, in 2014, around 69% of adults aged between 35 and 44 have lost at least one permanent tooth due to unsuccessful root canal, to an accident or by tooth decay. Thus, there is a rise in the practice of dental implants placed each year by 100,000 to 300,000, which is similar to the numbers of artificial knee and hip joints placed per year.
Furthermore, rising prevalence of chronic degenerative diseases and stringent regulations pertaining to sterilization of medical device packaging are the other factors that drive the growth of the medical implant sterile packaging market. However, inappropriate packaging of boxes for medical devices contaminate the devices while transportation and storage causing financial loss thereby, hindering the growth of medical device sterile packaging market.
Detailed Segmentation:
By Product Type:
Clamshell
Pouches and Bags
Blisters
Tubes
Vials
Others
By Application:
Spinal Implants
Reconstructive Joint Implants
Hip Joints
Knee Joints
Elbow Joints
Others
Extremity Braces and Support
Knee
Foot/Ankle
Hand
Elbow/Wrist
Dental Implants
Cardiovascular Implants
Others
By Material Type:
Plastic
Paper
Foils
Others
The major players in medical implants sterile packaging market are Beacon, SteriPack, Wipak, Oliver- Tolas, Rexam, Oracle Packaging, Riverside Medical Packaging, West Pharmaceutical Services, Amcor, Rollprint Packaging Products, and Sealed Air Corporation. The key players are focusing on strategic mergers and acquisition and development of innovative packaging systems.
For instance, Amcor has launched an innovative packaging technology in 2016, known as Fortis sterile breather bag (an uncoated Tyvek header bag), which delivers strength, sustainability, and tear resistance to hold sharp, heavy, and bulky packs in contrast to conventional header bags. Fortis header bags opening allows aseptic removal of contents easier thereby, reduces the risk of contamination to the sterile field.
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Some of the major players involved in global medical implants sterile packaging market are Beacon, SteriPack, Wipak, Oliver- Tolas, Rexam, Oracle Packaging, Riverside Medical Packaging, West Pharmaceutical Services, Amcor, Rollprint Packaging Products, and Sealed Air Corporation.
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Hemodynamic Monitoring Systems Market 2017 - Industry Growth, Size, Trends and Forecast to 2025

Hemodynamics monitoring systems market is expected to gain significant traction over the forecast period, owing to launch of novel monitoring systems by manufacturers. For instance, in 2016, Siemens Healthineers launched a new version of Sensis hemodynamic system at the Annual Scientific Session and Expo of the American College of Cardiology (ACC). Sensis Vibe aids in hemodynamic recording and documentation system in the cardiovascular hybrid operating room (OR) with the new HemoBox signal input unit.
Non-invasive and minimally invasive monitoring systems are gaining significant traction, as the use of non-invasive technique proves to be beneficial to determine the health condition of the patient and decide whether the patient can benefit from invasive techniques or the monitoring can suffice with the use of non-invasive techniques itself. Manufacturers are therefore, focused towards manufacturing systems that are novel with innovative technologies, in order to maintain their position in the market.
For instance, in June 2014, Edwards Lifesciences Corporation received U.S. Food and Drug Administration’s (FDA) clearance for its hemodynamic monitoring ClearSight system, which is a non-invasive monitor that provides clinicians access to blood volume and blood flow information for patients at moderate or high risk of post-surgical complications. In March 2017, LiDCO Group Plc introduced its next generation monitor platform in Europe. In addition to the sleek new look, the product has significant improvements in operating system and graphical user interface, and has next version of unity software with added features and functionality. In September 2017, Fysicon received FDA approval for QMAPP hemodynamic monitoring system that features up to 32 bipolar intra-cardiac channels for electrophysiology procedures.
Market players are focused on expansion of their product portfolio and geographic reach by adoption of inorganic strategies such as mergers and acquisitions, to maintain their positions in the market. For instance, in July 2016, Cheetah Medical signed a supplier agreement with Allina Health, which is a not-for-profit healthcare system that runs hospital network in areas such as Minnesota and western Wisconsin. Through this contract, Cheetah Medical would provide hemodynamic monitoring solutions to guide volume management decisions in septic patients across the Allina Health hospital network.
Moreover, in May 2016, LiDCO and ICU Medical signed distribution agreement to sell the LiDCO IM non-invasive hemodynamic monitoring system in U.S. LiDCO IM is a specially configured hemodynamic monitor produced exclusively for ICU Medical that works solely in conjunction with LiDCO’s non-invasive module.
Detailed Segmentation:
By Product Type:
Monitoring Systems
Disposables
Probes
Airflow Sensors
Others
By Monitoring Type:
Invasive Hemodynamics Monitoring
Non-Invasive Hemodynamic Monitoring
Minimally Invasive Hemodynamic Monitoring
By End User:
Hospitals
Catheterization Labs
Ambulatory Surgical Centers
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Key players are focusing on developing novel and innovative products, to sustain in the hemodynamics monitoring systems market. For instance, in March 2017, Teleflex announced 510(k) clearance by the Food and Drug Administration and both the U.S. and international commercial launch of the Twin-Pass Torque Dual Access Catheter. Moreover, in May 2016, Deltex Medical Group Plc introduced TruFlow in the U.K., which is wider beam, single patient disposable probe, the reconfigured probe tip design that creates a wider ultrasound beam at the focal point in the aorta.
Key players operating the global hemodynamics monitoring systems market include Edwards Lifescience Corporation, LiDCO Group, Plc, PULSION Medical Systems SE, Cheetah Medical, Inc. ICU Medical, Inc., Deltex Medical Group Plc, and Teleflex, Inc.
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PET-CT Scanner Device Market Growth Prospects Analysis - 2026


A positron emission tomography (PET) - computed tomography (CT) scan reveals information about both the structure and function of cells and tissues in the body during a single imaging session. In recent times, majority of PET scans are performed on instruments that are combined with PET and CT scanners. The combined PET-CT scans provide images that identify the anatomic location of abnormal metabolic activity within the body. The combined scans have been shown to provide more accurate diagnoses than the two scans performed separately.

The diagnosis of various diseases such as cancer, heart diseases, and certain brain disorders require the use of both PET and CT scans. PET scanners measure metabolic activity, whereas CT scanners highlight anatomical features. The risk to poor superimposition of separate imaging is reduced and the hybrid PET-CT process lessens burden on the patient by simplifying the scanning process. The use of PET-CT scanner hybrids combine the strengths of two well-established imaging modalities and helps in accurate diagnosis, localizing, and monitoring of the disease. Moreover, PET-CT scanners can record the images in extremely short time (less than a minute).


The global PET-CT scanner device market size was valued at US$ 1.9 billion in 2017 and is expected to witness a CAGR of 5.1% over the forecast period (2018 – 2026).

Increasing prevalence of chronic diseases and rising geriatric population is expected to drive the PET-CT scanner device market revenue

Rising prevalence of infectious and chronic diseases such as cancer and heart disease across the globe and increasing demand for effective diagnostic systems is expected to drive the PET-CT scanner market size. According to the National Centre for Health Statistics, 2011, heart disease is the leading cause of death in the U.S., killing over 600,000 people each year.

According to the International Agency for Research on Cancer (IARC), in 2012, an estimated 14.1 million new cancer cases were reported, globally. Among these, the most common form of cancer was lung cancer (13%), breast cancer (11.9%), and colorectal cancer (9.7%). According to the Centers for Disease Control and Prevention (CDC), February 2018 data, around 22,000 men and 9,000 women suffer from liver cancer, and around 16,000 men and 8,000 women die due to liver cancer, every year in the U.S.

PET-CT Scanner Device Market - Regional Insights

On the basis of region, the global PET-CT scanner device market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold dominant position in the global PET-CT scanner device market, owing to rising number of traumatic brain injury cases in the U.S. For instance, according to the Centers for Disease Control and Prevention (CDC), in 2013, around 282,000 people were diagnosed with brain injury and around 50,000 people died due to traumatic brain injury in the U.S. It is estimated to be a major cause of disability and death in the U.S.


PET-CT Scanner Device Market - Competitive Landscape

Key players operating in the global PET-CT scanner device market include General Electric Co., Hitachi, Ltd., Mediso Ltd., Koninklijke Philips N.V., PerkinElmer, Inc., Positron Corporation, Siemens AG, Shimadzu Corporation, Toshiba Corporation, and Yangzhou Kindsway Biotech Co. Ltd. Manufacturers are continually bringing in new PET/CT design. New technology enables more precise measurements of metabolic processes and data quantification, including assessment of cancerous tissue, neurologic disease, and cardiac blood flow (perfusion).

Detailed Segmentation:

Global PET-CT Scanner Device Market, By Detector Type:
  • FluroDeoxyGlucose (FDG)
  • 62CU ATSM
  • FMISO
  • Gallium
  • Thallium
  • Others

Global PET-CT Scanner Device Market, By Setting:
  • Fixed
  • Mobile

Global PET-CT Scanner Device Market, By Application:
  • Cardiology
  • Oncology
  • Neurology
  • Others


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Ursodeoxycholic Acid Market Projections of Trends and Growth till 2026


Ursodeoxycholic acid (UDCA) is a bile acid taken as either a tablet or liquid to treat gallstones and to treat and prevent progression of cystic fibrosis-related liver disorders. UDCA modifies the bile acid pool by decreasing levels of hydrophobic bile acids while increasing proportion of nontoxic hydrophilic bile acids. UDCA can delay development of gastroesophageal varices and progression to cirrhosis. Moreover, it can improve long-term survival in patients with primary biliary cirrhosis.


Significant improvement in liver health can be achieved through UDCA therapy in patients with intrahepatic cholestasis of pregnancy, primary sclerosing cholangitis, nonalcoholic fatty liver disease, cystic fibrosis-associated liver disease, total parenteral nutrition-induced cholestasis, graft related liver disease, and in some pediatric cholestatic liver diseases.

The global ursodeoxycholic acid market size was valued at US$ 457.3 million in 2017 and is expected to exhibit a CAGR of 10.1% over the forecast period (2018 – 2026).

Increasing prevalence of gall stones and cystic fibrosis to propel the ursodeoxycholic acid market growth

Ursodeoxycholic acid is being increasingly used for treatment of chronic cholestatic liver diseases. Increasing prevalence of cystic fibrosis and gall stones is the major factor driving growth of the global ursodeoxycholic acid market during the forecast period. According to the Cystic Fibrosis Foundation 2015 data, around 30,000 people suffered from cystic fibrosis in the U.S. Moreover, around 1,000 new cases of cystic fibrosis are diagnosed in the country, annually. According to the American Gastroenterological Association 2017 report, gallstones is affecting 10-15% of the U.S. population annually, which accounts for around 25 million people.

Increasing research studies on ursodeoxycholic acid to bolster the market growth

Increasing research studies conducted on application of ursodeoxycholic acid (UDCA) in other disease indications is expected to fuel growth of the global ursodeoxycholic acid market. According to the University of Sheffield August 2018 study, UDCA improves mitochondrial dysfunction, which is known to be a causative factor for both sporadic and familial Alzheimer’s disease.

According to the Cure Parkinson’s Trust, U.K. 2018 article, researchers demonstrated that UDCA could protect dopamine cells grown in culture from apoptosis, or programmed cell death, by regulating a specific cell survival pathway.


Key Players

Major players operating in the global ursodeoxycholic acid market include Dipharma Francis Srl, ERREGIERRE S.p.A., Grindeks, Industria Chimica Emiliana, Mitsubishi Tanabe Pharma Corporation, Zhongshan Belling Biotechnology Co., Glenmark Pharmaceutical Limited, Abil Chempharma Private Limited, Biotavia Labs Pvt Ltd, Daewoong Bio Inc., PharmaZell GmbH, and Suzhou Tianlu Bio-pharmaceutical Co., Ltd.

Detailed Segmentation:

Global Ursodeoxycholic Acid Market, By Dosage Form:
  • Solid Dosage Form
  • Liquid Dosage Form

Global Ursodeoxycholic Acid Market, By Mode of Extraction:
  • Synthetic
  • Biological

Global Ursodeoxycholic Acid Market, By Application:
  • Gallstones
  • Cystic Fibrosis
  • Liver Cirrhosis
  • Others


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Wednesday 17 July 2019

Nonalcoholic Steatohepatitis Treatment Market Report Explored in Latest Research to 2026


Nonalcoholic steatohepatitis (NASH) is a form of nonalcoholic fatty liver disease (NAFLD) in which a person have hepatitis and inflammation of the liver, and can cause liver damage. NASH can lead to complications, such as cirrhosis and liver cancer. Patients with NASH have high chance of mortality due to liver-related causes such as liver failure.

Lifestyle modification, including change in diet and exercise, is the basic therapy recommended for nonalcoholic fatty liver disease. However, in some cases lifestyle modification is difficult to achieve and to sustain, and therefore required other treatments including medicine.


Currently available drugs for the treatment of NAFLD were historically been given for other indications. For instance, Orlistat, a gut lipase inhibitor, is indicated for decrease in the dietary fats absorption. According to the National Center for Biotechnology Information (NCBI) 2017 study, Orlistat has been approved for treatment of obesity and is available over the counter in the U.S. for weight loss. Orlistat-mediated weight loss is related with reduction in hepatic steatosis.

The global nonalcoholic steatohepatitis treatment market size was valued at US$ 1,119.9 million in 2017 (based on existing approved therapies anti-diabetics, vitamins, dietary supplements, and others) and is expected to witness a CAGR of 42.7% over the forecast period (2018 – 2026).

Rising incidence of nonalcoholic steatohepatitis and strong product pipeline are expected to drive the nonalcoholic steatohepatitis treatment market revenue

Nonalcoholic steatohepatitis has become one of the most common liver-related health problems. The condition has been linked to an unhealthy diet and weight gain, but it can also be observed in non-obese individuals. Increasing prevalence of insulin resistance, and obesity is expected to fuel the nonalcoholic steatohepatitis treatment market during the forecast period.

According to an article published in Lancet, globally, prevalence of overweight and obesity combined has risen by 27.5% for adults between 1980 and 2013. According to the National Health and Nutrition Examination Survey (NHANES) 2014 data, in U.S. the percentage of obesity is higher in women, i.e. 40%, than in men, 35%.


Nonalcoholic Steatohepatitis Treatment Market - Regional Insights

On the basis of region, the global nonalcoholic steatohepatitis treatment market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America and Europe nonalcoholic steatohepatitis treatment market is expected to foresee significant growth owing to increasing incidence of obesity and fatty liver.

Nonalcoholic Steatohepatitis Treatment Market - Competitive Landscape

Key players operating in the global nonalcoholic steatohepatitis treatment market include AstraZeneca Plc., Conatus Pharmaceuticals, Enzo Biochem, Inc., GENFIT SA, Galmed Pharmaceuticals Ltd., Gilead Science, Immuron Ltd., Intercepts Pharmaceuticals, Novo Nordisk, Raptor Pharmaceutical Corporation, and Tobira Therapeutics, Inc.

Detailed Segmentation:

Global Nonalcoholic Steatohepatitis Treatment Market, By Drug:
  • Cenicriviroc
  • Elafibranor
  • Ocaliva (Obeticholic Acid)
  • Selonsertib

Global Nonalcoholic Steatohepatitis Treatment Market, By Distribution Channel:
  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy

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Endocrine Testing Market - Industry Growth, Size, Share, Outlook and Forecast 2018-2026

Companies are launching innovative products to cater the end user need and increase the market footprint in the endocrine testing market. In 2017, Beckman Coulter Diagnostics received FDA clearance of its automated Access AMH immunoassay for in vitro diagnostic (IVD) use. AMH test helps healthcare providers in the assessment of a woman's ovarian reserve, thereby aid in the clinical management of women facing infertility or women planning to become pregnant later in life. The Access AMH assay is a paramagnetic particle chemiluminescent immunoassay for the quantitative determination of AMH levels. The test can be used in conjunction with other clinical and laboratory findings such as antral follicle count, before starting fertility therapy. Companies are also undergoing strategic collaboration to increase market share. For instance, in 2017, Quest diagnostics and Walmart collaborated, under which Quest would open laboratory testing services at 15 Walmart locations initially to gradually increase same.
Endocrine testing allows profiling of blood concentration of the various endocrine hormone. Over secretion and under secretion of endocrinal hormones results in to development of endocrinal disease. Various endocrinal disease such as hypothyroidism, hyperthyroidism, infertility, polycystic ovarian syndrome, hypo/hyperadrenocorticism, hypogonadism, diabetes, Multiple endocrine neoplasia I and II, Cushing’s disease, Gigantism (acromegaly) and other growth hormone problem and precocious puberty( Early Puberty). Endocrine diseases are caused due to various reasons such as problem in endocrine feedback system, disease condition, and failure of stimulation of glands to release hormones, tumor of an endocrine gland, genetic disorders, infection and physical trauma to an endocrine gland.
Increasing prevalence of these disease especially hypothyroidism, infertility, and diabetes are expected to drive growth of the global endocrinal testing market. According to study published by Centre for Disease Control and Prevention (CDC), in 2017, around 100 million (30.3 million diabetes and 84.1 million prediabetes) U.S. adults were suffering from diabetes or prediabetes condition. According to American Thyroid Association, 2017, around 12% of U.S. adults are estimated to develop thyroid disease in their lifetime. Postmenopausal osteoporosis caused due to reduced estrogen production after menopause leading to low bone mineral density and increased risk for fracture risks. It is estimated that osteoporosis affects around 10 million American adults annually, 34 million people are at high risk of it due to low bone mass, according to study published by BMC Endocrine Disorder in February 2018.
Key players are undergoing strategic mergers, acquisitions, and collaborations in order to maintain leading position in market and to tap the new market. In August 2017, North West London Pathology under National Health Service Trust and Abbott Laboratories signed contract worth US$ 252 million under which Abbott Laboratories will supply all analytical equipment and consumables, this contract would manage 26 million tests annually. In 2017, Abbott Laboratories received the U.S. Food and Drug Administration (FDA) 510(k) clearance for its Alinity ci-series instruments for clinical chemistry and immunoassay diagnostics. In April 2018, Beckman Coulter launched its Access Sensitive Estradiol assay in the U.S. market, also made available its assay in the most of global markets. This test accurately detects estradiol levels in women, children, and men using low sample. Company also launched Anti-Müllerian Hormone (AMH) assay in 2017, which helps in clinical management of women suffering from infertility. In 2016, company received FDA clearance and commercially launched new Access TSH (3rd IS) assay.
Key players operating in the endocrine testing market include Abbott Laboratories, Thermo Fisher Scientific, Beckman Coulter, Inc., Siemens Healthineers, bioMérieux SA, Agilent Technologies, Bi-Rad Laboratories, AB Sciex, F-Hoffmann La Roche AG, Quest Diagnostics, and others.
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Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.
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