Ambulatory Services Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2025

Ambulatory care refers to the medical services provided on an outpatient basis without hospitalization or other medical facility. Outpatient services include physician and dentist offices, medical laboratories, and home healthcare. Ambulatory care service is one of the major contributor to the hospital revenue and to the performance of the health care system. Ambulatory care provides diagnosis, observation, consultation, treatment, intervention, and rehabilitation services to patient with advanced medical treatments. In addition, telephone consultations, rehabilitation visits, and emergency visits to the patients is expected to attract more patients towards the services, offering greater contribution to financial outcome.

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Cost saving surgeries drives the growth of the global ambulatory services market

According to the Centers for Medicare and Medicaid Services in 2016, approximately 35 million ambulatory surgical visits and 20 million surgical procedures were performed in hospital outpatient departments (HOPDs), with 15 million surgeries performed in ambulatory surgery centers (ASCs). Also, Medicare payments to ASCs have increased by 24% from $2.9 billion in 2007 to $3.6 billion in 2012. The factors driving the growth of ambulatory services include, rising government funding offering team-based primary care, cost-saving surgeries compared to the hospitals, and government investment for ambulatory care facilities. Additionally, the growing prevalence of chronic diseases with increasing geriatric population, advancement in technology, and new reimbursement rules by the government offering economic advantage are the factors leading to the growth of the global market. Also, the demand for minimally invasive surgeries, faster patient recovery with shorter healing time, inexpensive surgical charges, and well equipped ambulatory service centers is expected to drive the market in the forecast period. However delayed diagnosis, ineffective communication, and incidence of adverse drug events are restrains for ambulatory services market.

Hospital-based ambulatory surgical centers segment is expected to witness higher growth rate owing to value added services

The global ambulatory services market is segmented on the basis of center, modality, service, application and geography.

On the basis of centers, the global ambulatory services market is segmented into:

• Single Specialty Centre
• Primary Care Offices
• Outpatient Departments
• Emergency Departments
• Multi-Specialty Centre

On the basis of modality, the global ambulatory services market is segmented into:

• Freestanding Ambulatory Surgical Centers
• Hospital-Based Ambulatory Surgical Centers

On the basis of services, the global ambulatory services market is segmented into:

• Diagnostic Services
• Surgical Services

On the basis of applications, the global ambulatory services market is segmented into:

• Gastroenterology
• Ophthalmology
• Orthopedics
• Pain/Neurology
• Urology
• Dermatology
• Others

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Introduction of outpatient strategies is expected to accelerate the ambulatory services market in Asia Pacific

Regional segmentation of the global ambulatory services market by Coherent Market Insights comprises North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. According to the National Center for Health Statistics estimates in 2017, the number of outpatient surgery visits in the U.S. is increased from 2006 to 2016, from 20.8 million to 34.7 million visits, thereby raising the demand for ambulatory services. North America is expected to dominate the ambulatory services market owing to cost-saving offers eliminating hospital stays, shift of aging population to outpatient care, and expansion of network with physicians and healthcare providers. For instance, the partnership of Tenet Healthcare and United Surgical Partners International (USPI) in 2015 resulted in undertaking 20 imaging centers, 265 short-day surgical facilities with 4000 physicians. The demand for ambulatory services in Europe is expected to increase owing to event organizations by British Association of Day Surgery and Healthcare Conferences UK, to create awareness among patients and to improved quality of surgery. Asia-Pacific is expected to grow drastically in the forecast period owing to the increasing healthcare issues with rising incidence of chronic diseases, and government initiation to introduce outpatient strategies. For instance, the launch of mobile apps by China and Japan are providing medical knowledge and easy booking for outpatient appointments.

Comprehensive medical services offered by the keyplayers fuels the demand of ambulatory services market

Key players operating the global ambulatory services market include Symbion, IntergraMed America Inc., AmSurg Corp., Terveystalo Healthcare and DaVita HealthCare. The strategies applied by the key players include mergers and collaborations to offer comprehensive medical services. For instance, the acquisition of Premier Emergency Medical Specialists (PEMS) by AmSurg in 2015 marked its entry into emergency medicine specialty. Other vendors include SurgCenter, LVL Medical Group, Fresenius Kabi, Apria Healthcare and Healthway Medical Corporation Limited.

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Powered Surgical Instruments Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2025

Powered surgical instruments are precisely designed surgical instruments used to reduce time of surgical procedures and give consistent performance and functionality. These instruments are powered by external sources such as electricity or batteries. The advancements in the conventional powered surgical instruments has increased their use in numerous surgical areas such as in neurosurgery, orthopedic surgery, otology, dental surgery and some others. Every powered surgical instrument consist of a power source and many hand pieces which are required to perform specific functions. Development in the interchangeable accessories has made the surgical procedures safer and faster. Number of companies, physicians, and dentists are contributing to rapidly growing powered surgical instruments market.

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Rising medical tourism globally is an important factor propelling the growth of powered surgical instruments market

According to Health Research Funding (HRF) in U.S., around 400,000 robotic surgeries were performed among all type of surgeries in 2012 and the cost of these surgeries is increasing by 25% every year. The other factors fuelling to the growth of powered surgical instruments market include rising geriatric population, the growing number of patient with chronic diseases such as cancer, cardiovascular diseases, orthopedic conditions, and neurological diseases. Additionally, factors owing to the growth of powered surgical instruments market include, medical tourism, increased healthcare expenditure, rising cases with surgical procedures, growing accessibility to healthcare facilities, and rapid advancement in technology However, the factors that might hinder the growth of powered surgical instruments market include lack of skilled persons to handle these instruments, stringent policies to reduce the healthcare cost, absence of sterilization processes, and lack of quality assurance. Whereas the untapped market in emerging countries is expected to provide numerous opportunities for the growth of powered surgical instruments market.

Electric powered surgical instruments accounted for the maximum share in powered surgical instruments market due to their lower prices and applications in numerous surgical areas

The global powered surgical instruments market is segmented by power source, application, product, and region

On the basis of power source, the powered surgical instruments market is segmented into

• Electric
• Pneumatic
• Battery

On the basis of applications, the powered surgical instruments market is segmented into

• Neurology
• Orthopedic
• ENT
• Oral
• Thoracic

On the basis of product type, the powered surgical instruments market is segmented into

• Cables
• Console
• Cart
• Drill
• Saw
• Reamer
• Battery
• Blade
• Others

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Increase in medical tourism fuelling to the growth of powered surgical instruments market in Asia Pacific

Regional segmentation of powered surgical instruments market by Coherent Market Insights comprises of North America, Latin America, Europe, Asia Pacific, Africa, and Middle East. North America dominates in the power surgical instruments market due to the presence of well-established healthcare facilities  and rise in geriatric population.. Asia Pacific is also expected to propel in the powered surgical instruments market owing to factors such as increase in accessibility to healthcare facilities, rising medical tourism, and increase in prevalence of chronic diseases with requirement of surgical procedures.

Major industry players are involved in the expansion of product portfolio and geographical presence to hold the major share in the powered surgical instruments market

Key industry players operating in the Powered surgical instruments market include Johnson & Johnson, B. Braun Melsungen AG, Stryker Co., Medtronic Incorporated, Smith & Nephew, Conmed Co., and Zimmer Holdings. The major industry players are trying to expand their product portfolio and opting for geographical expansion to lead in the powered surgical instruments market. For instance, Stryker Co. has expanded product portfolio that include small bone, large bone, and high speed powered surgical instruments and accessories. The new players in the powered surgical instruments market might adopt the strategies such as market penetration, market diversification, and product innovation and development.

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Smart Home Medical Device Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2024

Post-discharge care plays an extremely important role in ensuring speedy and effective recovery of the patient. This is especially a matter of concern for the elderly as well as pediatric population who mostly spend their time at home and are usually dependent on someone else to ensure continued care. However, due to busy lifestyle of the populace in developed and emerging economies, post-discharge care is often hampered. This concern of family members as elderly people living alone is expected to favor growth of the market for smart home medical devices, such as fall detection system, bathroom sensors, monitoring and detecting systems and assisting systems. According to a Welfare Ministry Survey, in 2016, there were around 6.24 million people aged 65 and above were living alone in Japan. The increasing lonely deaths in the region is also a vital factor that is expected to favor the smart home medical device market.

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Global smart home medical device market taxonomy

The global smart home medical device market is classified on the basis of following segments:

Product Type:

Detection and monitoring systems

• Asthma detection kit
• Glucose monitoring system
• Others (blood pressure, weight variations)

Back therapy kit

Digital pills

Wearable

• Clothes
• Wrist watches
• Alert patch
• Smart contact lens

Others

• Mattress
• Bathroom accessories

Applications:

• Medication Management
• Glucose management
• Diagnoses
• Therapy
• Assistance
• Infant care
• Telehealth management
• Others (feeding, voiding)

Data Storage

• Cloud
• On-premises

Modality

• Benchtop
• Wearable
• Standalone

Growing internet penetration favors growth of smart home medical devices market:

Smart home medical device is latest and futuristic approach towards making life easier and secure. This revolutionary step by the medical devices company has affected the healthcare industry and the adoption rate for such technology in a positive way. While most consumers and healthcare organizations were skeptical about the technology, the scenario is rapidly changing, with higher adoption rate of such devices, a trend that is expected to continue over the forecast period. Furthermore, the wide availability of the smart home medical devices is a crucial block to fill the loop hole for acceptance of such devices and services. Easily available personal monitoring system and other electronic devices are expected to favor rise in adoption of smart home medical devices. Smart home basically defined as the residence that uses controllers to integrate the functions of the device installed at home. The controllers are connected through a computer that is connected via internet and the data of the respondent is recorded on cloud or on-premises data bank, which can be further monitored by the physician or caretaker accordingly.

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Growth in adoption of health caregiving is expected to underpin the smart home medical device market

According to American Association of Retired Persons (AARP), in 2016, around 80% growth has been observed in the medication management segment in the health caregiving market, which in turn is expected to support growth of the smart home medical device market in the near future. Medical technology utilized in home care settings, where the caregivers are active, ranges between complex and simple materials that are also used for administering first aid to sophisticated devices and advanced medical treatment. The products involved in home care settings can vary from tiny wireless devices to massive machines. Smart home medical devices such as blood pressure measuring equipment, sugar level measuring equipment and devices are widely used.

Highly fragmented market due to dominance of ICT organizations in smart home medical device manufacturing

The global smart home medical device market is highly fragmented market as encompasses pharmaceuticals, healthcare and information and communication technology industries. Growth in internet of things segment and its acceptance globally is expected to support the market for smart home medical device. Although, it is a difficult task to align the technology to the human vitals, incorporating the appropriate features into a medical device that are utilized by the patient or the care recipient at home is the most challenging factors for such devices. Major players involved in the smart home medical device market include ViVO Smart Medical Devices Ltd., Health Care Originals, Hocoma AG, VitalConnect, Proteus Digital Health, Cyrcadia Health, Qardio, Inc., and Neurometrix.

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Cell Lysis Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2025

Cells are defined as the basic unit of life that can replicate independently also referred to as the building blocks of life. Cells contain biomolecules such as proteins or nucleic acids present in the cytoplasm and enclosed within a membrane.

Cell lysis is a process in which a cell membrane is ruptured due to some external forces or conditions such as viral infection or osmosis, resulting in the release of cell contents,  thus  resulting in subsequent death of the cell. In industries and research laboratories,  cell lysis is often used to break open the cell to study its internal components. The  two methods through which cell lysis can be achieved include mechanical and chemical methods. Mechanical cell lysis method includes high shear mixing, sonication, freeze or thaw cycles, traditional homogenization, grinding, and high pressure homogenization whereas, chemical lysis method comprises of osmotic lysis, and the use of detergents, chelating agents, and chaotropic agents.

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The increase in protein purification studies/concept to boost the cell lysis market

The major factors contributing to growth of the cell lysis market are increase in research and development activities in industries. The research activities being carried out  in the biotechnology and pharmaceutical industries are related to protein, DNA, and RNA, to help explore prospects of novel biotherapeutic and pharmaceutical drugs. The extraction of proteins or nucleic acid is not possible without cell lysis, thus driving growth of the market. The other factors driving the cell lysis market growth include the increasing number of cancer cell studies, lung diseases, biotechnology firms, and growing focus on personalized medicine. However, one of the biggest challenges that the market is coping with is high costs associated to cell-based research.

Cell lysis market can be segmented on the basis of product type, instruments, cell type, applications, end-user, and geography

On the basis of product type, the cell lysis market is segmented into:

• Reagents And Kits
• Enzymes
• Detergent Solutions
• Other Reagents And Kits
• Beads
• Disposables

On the basis of instrument, the cell lysis market is segmented into:

• Sonicator
• Homogenizer
• Other Instruments

On the basis of cell type, the cell lysis market is segmented into:

• Mammalian Cells
• Microbial Cells
• Other Cells

On the basis of applications, the cell lysis market is segmented into:

• Enzyme Engineering
• Protein Labelling
• Protein-Protein Interaction
• Protein Purification

On the basis of end-user, the cell lysis market is segmented into:

• Research Laboratories
• Biopharmaceutical Industries
• Others

On the basis of regions, cell lysis market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is the largest region in the global market for cell lysis, followed by Europe. Asia Pacific is expected to be the fastest growing cell lysis market due to its increasing geriatric population, stabilizing economy, and development in the biotechnology and pharmaceutical sector.

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The medical research and genomics study on various diseased cells is expected to boost the cell lysis market

Becton Dickinson, one of the leading companies in the cell lysis market, provides medical technologies and innovative solutions globally, thereby improving the diagnosis of infectious diseases, cancer, medication management, and promotion of infection prevention. The other key players involved in the cell lysis market are Beckman Coulter, Bio- Rad Laboratories, Cell Signaling Technology, Thermo Fisher Scientific, Qiagen N.V., Qsonica, Merck KGaA, and F. Hoffman-La Roche AG.

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Biosimilars Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2025

Biosimilars are biological medical products which are the identical copies of the original products. Biosimilars are also termed as subsequent entry biologic or follow-on biologic. Biosimilars are expected to possess active properties, similar to that of officially approved original product at present. Biosimilars can be manufactured only when the patent for the original innovator product expires. Biologics or biosimilars are sensitive to changes in manufacturing process due to the higher molecular complexity. In 2010, The Food and Drug Administration (FDA) has gained the authority to approve biosimilars as a part of Patient Protection and Affordable Care Act. The approval process is based on thorough demonstration of similarity and comparability with the existing approved product. Biosimilars are generally derived from living cells of plants, animals, yeast, bacteria and viruses, through genetic engineering processes including controlled gene expression and recombinant DNA technology.

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Patent expiry of blockbuster drugs and increasing government initiatives for biosimilars promotion drives the growth of biosimilars market

The key factors driving the growth of biosimilars market are the increasing demand due to their cost-effectiveness, rising geriatric population, growing pressure to curtail healthcare expenditure, increasing government support and initiatives to develop and promote biosimilars, strategic collaborations to enhance productivity and clinical trial activities for biosimilars. According to the American Health and Drug Benefits in 2013, the average biosimilars sale was more than U.S. $1 billion annually. For instance the global sales was projected to be around U.S. $7.19 billion for Remicade (infliximab) and U.S. $5.98 billion for Avastin (bevacizumab), leading to the higher approval by the doctors and patients of biosimilars globally. Also, the early phase of biosimilars market, easy entry, high growth opportunity, agreement for improved reimbursements with insurance companies are further driving the biosimilars market. The expiry and termination of numerous blockbuster pharmaceuticals drugs like Humira, Enbrel and Remicade in the next 5 to 10 years is the primary driver providing significant opportunity for new players to enter the market.

Diabetes medicine and oncology segments are expected to attain faster growth during the forecast period

The global biosimilars market is segmented on the basis of product type, manufacturing type, application, end user and geography.

On the basis of product type, the global biosimilars market is segmented into:

• Monoclonal Antibodies
• Recombinant Hormones
• Anti-Inflammatory Agents
• Recombinant Growth Stimulators
• Immunomodulators

On the basis of by manufacturing type, the global biosimilars market is segmented into:

• In-house Manufacturing
• Contract Manufacturing Organizations

On the basis of application, the global biosimilars market is segmented into:

• Chronic & Autoimmune Diseases
• Oncology
• Blood Disorders
• Growth Hormone Deficiency Diseases
• Infectious Diseases
• Others

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Cost effective potential of biosimilars is the primary factor expected to boost the biosimilars market in Asia Pacific

Regional segmentation of the biosimilars market by Coherent Market Insights comprises North America, Europe, Asia-Pacific, Latin America and Middle East and Africa.  The first FDA approval biosimilar in 2015, Sandoz’s Zarxio has marked a promising hit of the biosimilars market across North America. According to the American Society of Health-System Pharmacists survey in 2013, about 99% of 214 surveyed pharmacy directors reported at least one oncologic drug shortage with the consequences of adopting the distribution of biosimilars to meet the rising demands.  Also, the demand for biosimilars is expected to gather momentum in North America owing to the rising prevalence of cancers, autoimmune diseases, kidney failures and growth hormone deficiency and increasing approval rates by FDA. The treatment for various diseases including diabetes, rheumatoid arthritis and types of cancers are anticipated to become affordable in developing countries like China and India, thus providing opportunities for major players in the Asia Pacific biosimilar market to expand during the forecast period. Additionally, the Asia-Pacific market is expected to witness higher growth owing to economic biopharmaceuticals or the low- cost of biosimilars, high adoption rate and consistent guidelines issued by the regulatory authority.

The increase in product extensions integrated with technological innovations is expected to intensify the competitive environment within manufacturers

Key players operating in the biosimilars market include Sandoz International GmbH, Apotex, Biocon, Zydus Cadila Healthcare, Celltrion and Pfizer. The leading manufacturers are focusing on outsourcing the production of biosimilar products with strategic collaborations to replace the existing expensive drugs. For instance, in August 2016, the FDA approval by Sandoz for the biosimilar Erelzi, used for treating multiple inflammatory diseases such as rheumatoid arthritis, plaque psoriasis, ankylosing spondylitis and juvenile idiopathic arthritis. The other prominent vendors include Hexal, Accord Healthcare, Harvest Moon Pharmaceuticals, Eli Lilly and Teva Pharmaceuticals.

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Pulse Oximeter Market by product type, and end-user - Global Industry Insights, Trends, Size, Share, Outlook, and Opportunity Analysis, 2017–2025

Major players operating in pulse oximeter market

There are few big brands that are expected to favor the growth of pulse oximeter market. The Apple watch used pulse oximeter technology for its heart rate monitor which has increased the market size of pulse oximeter. Key players operating in pulse oximeter market are CAS Medical Systems Inc., Covidien Plc, Masimo Corporation, Nihon-Kohden Corp., Nonin Medical Inc., Opto Circuits Ltd., Criticare Systems Inc., Mediaid Inc., Spacelabs Health care Inc., Philips Healthcare and Welch Allyn Inc.

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Pulse oximeter is a noninvasive device used for monitoring a person’s oxygen saturation (SO2). In its most common application mode, a sensor device is placed on thin part of the patient body, which is usually a fingertip or earlobe in adults and in case of infants it is placed across a foot. The pulse oximeter displays the percentage of blood that is loaded with oxygen. Pulse oximeter specifically measures the percentage of hemoglobin, the protein in blood that carries oxygen. Pulse oximeter is particularly convenient for continuous measurement of blood oxygen saturation noninvasively. Pulse oximeter can be used in any setting where patient’s oxygenation is not stable such as in intensive care, recovery, operating, emergency and hospital ward, pilots in unpressurized aircraft, patient at high altitude for assessment of any patient’s oxygenation and to determine whether there is need for supplemental oxygen.Furthermore, the simplicity of use and ability to provide continuous and immediate oxygen saturation values makes pulse oximeters of critical importance in emergency medicine or first aid. Pulse oximeter

Furthermore, the simplicity of use and ability to provide continuous and immediate oxygen saturation values makes pulse oximeters of critical importance in emergency medicine or first aid. Pulse oximeter are useful for patients with cardiac problem, respiratory problem and chronic obstructive pulmonary disease.

Moreover, pulse oximeter are used for diagnosis of sleeping disorders such as hypopnea and apnea. The pulse oximeter with portable battery are useful for pilots operating in a non-pressurized aircraft where supplemental oxygen is required. Pulse oximeter are also used extensively used by mountain climbers and athletes whose oxygen level may decrease at high altitude or with extensive workout.

Pulse Oximeter Market Taxonomy

By Product Type

• Table-top/Bedside Pulse Oximeters
• Fingertip Pulse Oximeters
• Wrist-worn Pulse Oximeters
• Handheld Pulse Oximeters
• Pediatric Pulse Oximeters

By End Users

• Hospitals
• Healthcare Facilities
• Ambulatory Surgical Centers
• Homecare

Driving forces for the growth of pulse oximeter market in the near future:

Enhancement in healthcare workers to efficiently adopt the improved and reliable detection algorithms, increasing awareness and high prevalence of diseases that require continuous monitoring are the driving forces of pulse oximeter market.

Furthermore, pulse oximeter market is also driven by technology advancements and also in expansion of clinical applications such as in critical care, childbirth, neonatal, surgery, anesthesia and pediatric care. Increasing demand for pulse oximeter is mainly linked to its portability, connectivity, and small size.

Moreover, increase in aging population according to International Journal of Health Policy and Management showed periodic increase during 2004-2012 of aging associated increase in hospitalization, which was pegged at 1.03 million globally. This in turn is expected to favor growth of the pulse oximeter market. Standardization of patient monitoring in clinical practice creates a highly conducive environment for growth of the global pulse oximeter industry. Growing use of alternate care facilities and development in R&D also drives the market of pulse oximeter. However, according to National Sleep Foundation, in 2012, around 40 million people in the U.S. suffered from chronic sleep disorder which suggest the increased use of pulse oximeter.

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Regional growth engines of the pulse oximeter market

According to Centers for Disease Control and Prevention (CDC) and American Academy of Pediatrics (AAP) in September 2014 mandatory critical congenital heart defects (CCHD) screening for new born is a key reason for dominance of U.S for market of pulse oximeter market. Asia Pacific is assumed to observe fastest growth in near future due to increase in investment of industry player in this region is a key reason for growth of market. According to The European Sleep Apnea Database (ESADA), of March 2014, the number of enrollment of patients has reached to 15,956 along with 5313 follow up visits which shows that pulse oximeter market is rising in Europe

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Neurostimulation Devices Market by application, product type, geography – Global Industry Insights, Trends, Outlook by 2025

Some of the major players in neurostimulation devices market are Virtual Medical Centre Inc Neurosigma, Boston Scientific Corporation, St. Jude Medical Inc., NDI Medical, electroCore LLC, Electro Medics, Endostim Inc., and NeuroPace, Inc.

Neurostimulation is therapy used for treatment and diagnosis of disorders of the nervous system. Neurostimulation devices include implantable and non-implantable devices, which deliver chemical, electrical or other agents that reversibly modify nerve cell activity and brain cells. Certain diseases do not respond or react to drug therapies; in such cases advanced neurostimulation devices are used as part of the treatment. Neurostimulation devices are surgically inserted into the patient organs and are controlled with the help of thin wires and leads.

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Neurostimulation is used to reduce chronic pains associated with conditions such as Parkinson’s disease, epilepsy, nociceptive pain, neuropathic pain, and depression. It helps improve quality of life of patients suffering from paralysis, obesity, and severe loss of sensory organs. Neurostimulation devices is a key element used in neural prosthetics for artificial vision, artificial limbs, hearing aids, and many more. Neurostimulator is the best therapeutic solution for pain associated with failed back surgery and diabetic neuropathy.

As per the data published by European Brain Council, worldwide around 6.3 million people were living with Parkinson’s disease in 2015 and the number is expected to increase steadily in the near future.

Intracranial stimulation, peripheral nerve stimulation (PNS), Spinal cord stimulation (SCS), deep brain stimulation, and motor cortex stimulation are among the most widely used neurostimulation devices. Spinal cord stimulation is widely used in failed back surgery, pain due to peripheral neuropathy, and pain due to low supply of blood to the limb, chest pain, urinary incontinence, and occipital neuralgia. The deep brain stimulation is generally use to treat Parkinson’s plus syndromes. PD is a neurodegenerative disorder in which brain cells progressively die.

Increase in the prevalence of diseases such as Parkinson’s disease (PD) expected to lead the growth of neurostimulation devices market

According to national institutes of health (NIH), around 50,000 people were suffering from Parkinson disease (PD) in the U.S. each year about half of a million people have the disease. North America account for the largest market for neurostimulation devices and is expected to retain its dominance through the forecast period. This is mainly attributed to high patient awareness level and high healthcare spending in the region. Asia Pacific is projected to be the fastest growing market, mainly due to high prevalence of PD in countries such as India and China.

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As per stats released by the World Health Organization (WHO), around 6.3 million people worldwide suffered from Parkinson’s disease in 2013. Furthermore, according to Anxiety and Depression Association of America (ADAA), in 2016, people suffering from anxiety disorders are highly treatable. According to the National Institute of Mental Health (NIMH),  10% to 15% worldwide women develop postpartum depression. Major depression includes bipolar disorder which are accompanied by delusions, hallucinations, or paranoia which is called as psychotic depression. These conditions can be effectively treated using neurostimulation devices. According to the National Alliance on Mental Illness (NAMI), around 20% of people in U.S are suffering with major depressive disorder develop psychotic symptoms hallucinations.

Essential Tremor (ET) leads to action tremor, with prevalence rate of up to 10% in the US. It is reported that 85% of the patient lifestyle is affected by this disease. This inadvertently creates a highly conducive environment for growth of the neurostimulation devices market.

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Neurostimulation devices market taxonomy:

Global Neurostimulation Devices Market by Type of Device

• Deep Brain Stimulators
• Gastric Electric Stimulators
• Sacral Nerve Stimulators
• Vagus Nerve Stimulators
• Spinal Cord Stimulators
• Others

Global Neurostimulation Devices Market by Application

• Parkinson's Disease
• Depression
• Essential Tremor
• Urinary and Fecal Incontinence
• Gastroparesis
• Others

On the basis of end user, the Global Neurostimulation Devices Market is classified into the following:

• Hospitals
• Rehabilitation Centers
• Medical Clinic

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Melanoma Treatment Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2025

Melanoma is a type of skin cancer that develops from the pigment cells known as melanocytes. It is caused due to high exposure to ultraviolet rays, which leads to sunburn, especially at high altitudes. Melanoma is categorized into three: cutaneous, mucosal, and ocular. Cutaneous affects the skin, mucosal affects the mucous membrane in the mouth and nasal passage, and ocular affects the eye. However, early detection of melanoma helps in the treatment and increase survival rates. According to the American Academy of Dermatology 2015 report, the prevalence of melanoma is increasing and spreads to other body parts as well. As it spreads to other body parts, its treatment becomes much more complex. The rare genetic conditions such as xeroderma pigmentosum also increase the risk of melanoma and it is diagnosed with the biopsy of any skin lesion.

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Melanoma Treatment Market Taxonomy:

The global melanoma treatment market is segmented as follows;

By Melanoma Type;

• Cutaneous Melanoma
• Mucosal Melanoma
• Ocular Melanoma

By Therapy;

• Chemotherapy
• Immunotherapy
• Targeted Therapy
• Surgical Treatment
• Pharmacological Treatment

Development of new drugs fuels the melanoma treatment market

Several drugs in the market have already received FDA approval for melanoma treatment and some are under development. Drugs such as seviprotimut-L by Polynoma’s, talimogene laherparepvec (T-VEC) by Amgen Inc., and zelboraf, by Roche and Genetech together for the treatment of cutaneous melanoma are under development. Selumetinib is under development by AstraZeneca for the treatment of ocular melanoma. In 2011, Yervoy, a monoclonal antibody drug was developed by Bristol-Myers Squibb for the treatment of melanoma and it is the first drug to receive FDA approval. Immunotherapy drugs include opdivo and keytruda, which got FDA approval and created new opportunities in melanoma treatment market. When chemotherapy fails to deliver results, targeted therapy is used, which include BRAF inhibitors. Targeted therapy has limited side effects in comparison with chemotherapy. According to Cancer Research Institute, in 2016, there were around 76,000 people diagnosed with melanoma in the U.S. The development of novel drugs and combination therapy with limited side effects and better survival rates is expected to fuel the melanoma treatment market growth. The increased focus on personalized medicine with a huge investment in anti-melanoma drugs is expected to create new opportunities in near future. However, high price of combination therapies and clinical trial with side effects act as restraints for the melanoma treatment market.

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Developed regions support the growth of melanoma treatment market

Melanoma treatment market, based on geography, is segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America dominates the melanoma treatment market due to the high prevalence of melanoma in the region along with well-developed healthcare facilities and increased research and development on melanoma drugs. Moreover, reimbursement policy and increase in per capita income are expected to fuel the melanoma treatment market. Europe is the second largest market and is expected to grow significantly in near future due to increase in melanoma cases and development of novel therapies. Asia Pacific is expected to exhibit moderate growth due to fewer cases of skin cancer, lack of awareness, and high cost of melanoma drugs.

Key Players in the Global Melanoma Treatment Market

Some of the key players identified across the value chain of global melanoma treatment market are Bristol-Myers Squibb, F. Hoffmann-La Roche Ltd., Genetech Inc., Novartis AG, Polynoma LLC, AstraZeneca, Amgen Inc., Sanofi, Merck & Co. Inc., and Takeda Pharmaceutical Company.

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Ophthalmic Devices Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2025

Ophthalmology refers to a branch of medical sciences that deals with the structural and functional defects of the eye. Ophthalmic devices are medical devices used in the treatment and identification of certain ocular deformities and deficiencies of the eyes. The global ophthalmic devices market is driven by eye disorders such as glaucoma, diabetic retinopathy, macular degeneration, and cataract and vision care devices. Ophthalmic devices are also used in various surgical processes such as ultrasound phacoemulsification for faster recovery rates and improved safety. A wide range of ophthalmic devices are available in the market from high complexity devices such as phoropters , ophthalmoscopes, retinoscopes and scanning laser polarimetry devices to low end products such as contact lenses, spectacles and lens cleaning and disinfecting solutions, Thus, the demand for ophthalmic devices is anticipated to be increasing significantly over the forecast period.

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Increasing prevalence of eye disorder is projected to fuel growth of the global ophthalmic devices market

According to the International Journal of Advanced Medical and Health Research 2015, cataract has been reported to be the major cause of blindness, affecting 17-18 million people worldwide, accounting for 39% of such cases. Following cataract, glaucoma is seen to be the second major reason causing blindness among people. According to the Glaucoma Research Organization, over 120,000 people are blind due to glaucoma accounting up to 9-12% of total blind cases. These massive numbers are basically the output of eye disorders prevalence in the geriatric population and changing food habits leading to nutritional deficits in the younger population. The ophthalmic devices can be used in order to treat cataract, glaucoma and several other eye disorders that could propel the global ophthalmic devices market.

The vision care devices segment dominating the global ophthalmic devices market in terms of over the counters sales

The global ophthalmic devices market is segmented on the basis of product type, disorder, and geographical region.

On the basis of product type, the global ophthalmic devices market is segmented as

• Diagnostic and Monitoring Devices
• Surgical Devices
• Vision Care Devices

Vision care devices witnesses maximum sale over the counter and therefore accounts for the largest share. Furthermore there is a rapid rise in number of people affected with eye disorders and increasing awareness among the populace about eye health and safety augments growth of the segment. According to The Vision Council, over 87% of people in the U.S. are reported to be using digital devices for over 2 hours per day, thereby developing eye strain, dry eyes, blurred vision, etc. These small eye related troubles can be sorted with the use of vision care devices in turn potentiating the global ophthalmic devices market. Moreover, rapid growth in the eye diseases such as cataract and glaucoma are resulting in potential growth of the surgical devices segment that would be required in the treatment of these disorders.

On the basis of disorders, the global ophthalmic devices market is segmented as

• Cataract Surgery Devices
• Refractive Surgery Devices
• Vision Care
• Ophthalmic Diagnostic Devices
• Vitreo Retinal Surgery Devices
• Glaucoma Surgery Devices

Emerging economies of Asia Pacific to boost global ophthalmic devices market growth in the forecast period

Based on regional segmentation, the global ophthalmic devices market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East and Africa. The North America is accounted to capture highest share in the global ophthalmic devices market owing to innovation and focus on diagnostic devices and surgery applications as well as higher market penetration levels. The emerging economies such as China, India, Japan and Brazil are estimated to gain an early momentum in the market as a result of massive investments by manufacturers.

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Governments in developing countries focusing towards eye safety and vision care thereby mushrooming the global ophthalmic devices market

The annual rise in the prevalence of eye disorders such as cataract, glaucoma and macular degeneration are the major drivers of the global ophthalmic devices market. Several other factors that are responsible to bolster the growth of ophthalmic devices market includes advent of technologically advanced minimally invasive surgery, rise in geriatric population and demand for surgical and diagnostic instruments. The growing occurrence of eye disorders in children will also add up to fuel the market growth. The governments in developing countries supporting to establish sophisticated healthcare infrastructure and eye care centers will in turn favor growth of the global ophthalmic devices market. However, the inadequate awareness among the developing nations regarding vision care and treatments related to eye disorders can inhibit the market growth.

The global ophthalmic market is very vast, rapidly growing as well as highly competitive. Some of the major players operating global ophthalmic market are Johnson and Johnson, Novartis AG, Bausch & Lomb Inc., Essilor International, Abbott Laboratories Inc., VisionCare Inc., Hoya Corporation, Canon Inc., Carl Zeiss AG, Topcon Corporation, Nidek Co Ltd., CooperVision AG and Alcon Inc. The players are sustaining their prime position in the global ophthalmic devices market due to consistency in launching of new ophthalmic devices and eye care products. Alongside, several other new entrants may also create growth opportunities and enhance the growth of the global ophthalmic devices market.

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Interventional Cardiology Devices Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2025

Interventional cardiology is the branch of cardiology that specifically deals with catheter based treatment of heart diseases, such as congenital heart defect (CHD), coronary artery disease, and aneurysm. This involves insertion of the catheter into femoral artery or any large peripheral artery or vein and through catheter whole procedure is performed by using fluoroscopy. Interventional cardiology has reduced the complications for patients as it provides, fast recovery, short hospital stay, and controlled bleeding. There is constant development in interventional cardiology devices, such as from bare metal stent to bio-absorbable stent. According to Centers for Disease Control and Prevention, which provides information about various diseases, there were around 40,000 children born with CHD in the U.S. in 2016. Interventional cardiology devices include catheters, guide wire, stents, filters, and balloons.

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Interventional cardiology devices market taxonomy:

By Product Type

• Stents
• Catheters
• Percutaneous Transluminal Coronary Angioplasty (PTCA) Balloons
• Intravascular Ultrasound System
• Inferior Vena Cava (IVC) Filter
• Percutaneous Transluminal Coronary Angiography (PTCA) Guide Wires
• Left atrial Appendage (LAA) Device

By Geography

• North America
• Latin America
• Europe
• Asia Pacific
• Middle East
• Africa

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Increased prevalence of cardiovascular diseases is expected to fuel the growth of interventional cardiology devices market

There is a continuous increase in geriatric population and obesity which is leading  to the increase in cardiovascular disease. For instance, as per United Nations report, there were around 901 million people of age 60 and above in 2015 and it is expected to reach 1.4 billion by 2050. Advancement in healthcare research, increasing patient awareness, and increase in the demand for minimal invasive surgery raise the demand for interventional cardiology devices. Interventional cardiology devices help interventional cardiologist to perform the procedure in short span of time, which reduces the risk and complication. The increase in obesity, geriatric population and lifestyle changes leads to the increase in coronary artery disease, for instance as per American Heart Association 2017 report, in the U.S. there was around 360,000 death caused due to coronary artery disease. With the prevalence of lifestyle diseases such as diabetes and hypertension has increased the cases of cardiovascular disorders. Continuous technological advancement in interventional cardiology devices and development of new systems with improved features such as new generation of drug eluting balloons and bio-absorbable stents are expected to support the growth in interventional cardiology devices market. Initiative taken by the Government to increase awareness about cardiovascular diseases and conduction of regular medical checkup camps has boosted the growth of market. Major challenges faced by interventional cardiology medical devices market is high manufacturing cost of these devices.

Developed regions support the growth of interventional cardiology devices market 

Interventional cardiology devices market is segmented into various geographical regions such as North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America leads the interventional cardiology devices market because of the large geriatric population and sedentary lifestyle leading to cardiovascular disorders. According to Population Reference Bureau 2016, there were around 40 million people of age 60 and above, and it is expected to reach 89 million by 2050 in the U.S. Europe is closely following the North America in interventional cardiology devices market followed by Asia Pacific. However, Asia Pacific is expected to expand significantly in near future because of emerging economies such as India and China due to the increase in cardiovascular diseases, increased healthcare expenditure, per capita income of individual and increase in geriatric population, which is expected to support the growth of interventional cardiology devices market.

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Key players to support the interventional cardiology devices market

There are various players present across the globe contributing to the interventional cardiology devices market. Some key players are Abbott, Terumo Medical Corporation, Boston Scientific Corporation, Cardinal Health, Medtronic, Cook Medical and B. Braun Melsungen AG. In 2017, Abbott acquired St Jude Medicals to increase the product pipeline, as St Jude Medicals are into atrial fibrillation, structural heart, heart failure and chronic pain and Abbott are leading in coronary inventions, which increase the market share and fuels the growth of interventional cardiology devices market.

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Atopic Dermatitis Drug Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2025

Atopic dermatitis, also known as eczema, is a condition in which skin becomes dry, itchy, and inflamed, which leads to redness, swelling, scaling, and crusting.  Atopic dermatitis is commonly found in children under one year. The exact cause of atopic dermatitis is undiscovered, but it is believed that it includes genetics, environmental exposure, immune system dysfunction, and problem with skin permeability. Dry climate is also a major cause of atopic dermatitis. This disease is non-contagious and easily diagnosed with signs and symptoms such as swelling and redness of skin. Many people with atopic dermatitis develop asthma and hay fever. Atopic dermatitis treatment involves photo therapy, steroid pills, calcineurin inhibitors ointment, biologic agents such as immunologic, monoclonal antibody, and dietary changes in case of food allergy.

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Topical steroids and development of new drugs fuel the atopic dermatitis drug market

Atopic dermatitis treatment majorly relies on topical steroids and hence the segment holds the largest market share. A lukewarm bath followed by the application of moisturizer helps in the treatment of atopic dermatitis. Immunomodulators and pimecrolimus are also used for the treatment of atopic dermatitis. According to the American Academy of Dermatology, in 2016, there were around 28 million people of all age groups affected by atopic dermatitis in the U.S. The expected launch of dupilumab, monoclonal antibody developed by Sanofi and Regeneron Pharmaceuticals Inc. in 2017, which is approved by FDA for the treatment of atopic dermatitis plays a major role in the treatment of the disease and supports the growth of atopic dermatitis drug market. In December 2016, the crisaborole ointment was approved by FDA for the treatment of mild atopic dermatitis. When such drugs are launched, FDA issues black box warning on the label of prescribed drug to warn users about the side effects. It is expected that new product launches in near future will significantly boost the atopic dermatitis drug market. This market offers opportunities to the companies involved in the development of novel drugs and therapies as there is an extensive need for developed medications with high safety and efficiency. Major challenges faced by atopic dermatitis drug market are side effects, high cost of treatment, and lack of good & safe therapeutics, which hinder the market growth.

Developed regions support the growth of atopic dermatitis drug market

On the basis of geography, the global atopic dermatitis drug market is segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America dominates the atopic dermatitis drug market due to increasing number of atopic dermatitis cases and high R&D investment for the development of atopic dermatitis drug. The increase in food and skin allergies raised the atopic dermatitis cases in infants, which in turn fuels the atopic dermatitis drug market growth. Europe is the second largest market for atopic dermatitis drugs followed by Asia Pacific. Asia Pacific is a flourishing market owing to the prevalence of atopic dermatitis and increased demand for drugs in emerging countries such as India and China. The market is expected to expand at a high rate in the near future, supporting the global atopic dermatitis drug market.

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Key Players in the Global Atopic Dermatitis Drug Market

Major players in the market use different strategies such as mergers and acquisitions in order to acquire high market share and attain a competitive edge. In 2016, Novartis AG acquired Ziarco, which adds oral atopic dermatitis drug to its product pipeline. Pfizer acquired Anacor Pharmaceuticals in 2016 allowing access to non-steroidal topical gel, crisaborole, approved by FDA for atopic dermatitis treatment. Some of the key players in the market are Bayer Healthcare, Valent Pharmaceutical Inc., Astellas Pharma Inc., Meda AB, and Novartis AG.

Atopic Dermatitis Drug Market Taxonomy

By End User;

• Hospitals
• Clinics
• Research Labs

By Route of Administration;

• Injectable
• Oral
• Topical

By Therapy;

• Photo Therapy
• Directed Therapy

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Guidewires Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2025

Guidewires are flexible and thin tubes that guide a catheter for placement in the diseased organ. Guidewires are used to open the target vessels, cross lesions and provide definitive interventional therapy to patients. Guidewires are the crucial components of vascular intervention with indispensable uses in the field of minimally invasive surgeries due to its capacity of rendering precise and effective results. Guidewires are of several types as various clinical presentations need different device features. An appropriate guidewire for a particular condition can improve device delivery, enhance crossing success, restrict expenses and limit the risk of vascular injury. Guidewires are mainly manufactured from stainless steel with an elastic coil tip to prevent blood vessel from damage. The guidewires are reusable products in nature with low cost stainless steel mainly used as a raw material by manufacturers. A robust range of wire configurations and tip shapes makes it possible for healthcare professionals in choosing the right tool for surgical procedures. Biomechanical properties of the guidewires in the medical device industry contributes to its rapid growth.

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Extensive use of guidewires in surgical interventions is expected to fuel the growth of guidewires market

According to the Journal of American College of Cardiology, an estimated 422.7 million prevalent cases of cardiovascular diseases were recorded globally in 2015, with 8.9 million deaths observed due to Ischemic Heart Disease (IHD). The higher occurrence of cardiovascular diseases is attributed to the shift in lifestyle habits including dietary irregularities and smoking which results in growing incidences of obesity, thus resulting in the global guidewires market demand. Also, the demand for guidewires is increasing by the rise in patient awareness about the advantages of minimally invasive procedures like decreased traumatic surgical experience, faster recovery, fewer post-surgery complications, reduced incision wounds and higher patient satisfaction. Additionally, growing acceptance of guidewires among medical practitioners, rising research and development investments and surging number of market entrants are the factors propelling guidewires market. Growing use of guidewires for diagnostic and interventional purposes of cardiological diseases is expected to stimulate guidewires market over the forecast period.

Coronary guidewires are largely used guidewires owing to the high volumes of minimally invasive coronary procedures

The global guidewires market is segmented on the basis of product type, application, end user and geography.

On the basis of product type, the global guidewires market is segmented into:

• Stainless Steel Guidewires
• Nitinol Guidewires
• Hybrid Guidewires

On the basis of application, the global guidewires market is segmented into

• Interventional cardiology
• Infusion therapy
• Vascular access
• Interventional neuroradiology
• Endourology
• Gastroenterology

On the basis of end user, the global guidewires market is segmented into:

• Hospitals
• Ambulatory Surgical Centers
• Others

The rise of peripheral vascular diseases fuels the guidewires market in Asia Pacific

Regional segmentation of the global guidewires market by Coherent Market Insights comprises North America, Europe, Asia-Pacific, Latin America, Middle East, and Africa. According to Centre for Disease Control and Prevention in 2016, approximately 8.5 million people in the U.S. have peripheral artery disease and is expected to reach 19 million by 2050. Thus, North America holds a dominant position in the global guidewires market. The major driving factors for the growth of the guidewires market in North America, include rise in lifestyle diseases such as heart attack, strokes, myocardial infarction, ischemic stroke, atherosclerosis and neuro vascular diseases. Asia Pacific market is developing at a rapid rate owing to economic development, improving healthcare amenities and government initiatives in the emerging economies. Also, a large group of patients suffering from peripheral vascular diseases leads to an increase in the endovascular procedures in densely populated countries of India and China.

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Rapid technological advancements like navigation with a magnetic guidewire is expected to created immense growth opportunities for industry participants

Key players operating the guidewires market are Boston Scientific Corporation, ASAHI INTECC Inc., Cordis Corporation and C.R. Bard. The launch of Glidewire product by Terumo is rapidly gaining popularity in the global market owing to its higher efficiency in vascular access and coronary intervention procedures.  Other leading vendors have adopted technological innovation and advancements for manufacturing novel guidewires in terms of flexibility, construction and tip retention are Terumo Corporation, Medtronic Inc., Abbott Laboratories, Covidienplc, Braun Melsungen and Cook Medical.

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Phosphodiesterase Enzyme Inhibitors Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2024

Phosphodiesterase are a diverse family of enzymes (11 isoenzymes) that play a key role in regulating intracellular levels of secondary messengers - cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate. These enzymes identified to be pharmacologically active in the 1950s, hydrolyses cyclic nucleotides to treat various diseases such as cardiovascular, respiratory and erectile dysfunction. Distinct distribution of all the types of isoenzymes has provided possibilities for selective target therapies.

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The global phosphodiesterase enzyme inhibitors market can be better analyzed by classifying it into two classes as selective phosphodiesterase enzyme inhibitors and non-selective phosphodiesterase enzyme inhibitors. Theophylline and papaverineare the two most commonly used non-selective phosphodiesterase enzyme inhibitors for treating a range of diseases (bronchodilation, cardiac disorder, etc.). Advent of selective phosphodiesterase enzyme inhibitors has made a great impact in the medical treatment sector. Increasing understanding of the individual PDE isoforms has and will result in the emergence of better therapeutic drugs. Viagra (Sildenafil) is the best example to substantiate the success and impact of PDE inhibitors.

Increasing product developments to further improvise the phosphodiesterase enzyme inhibitors market outlook

The global phosphodiesterase enzyme inhibitors market has recently gained traction on account of the blockbuster PDE 5 inhibitor brands, Viagra and Cialis. This has also encouraged pharmaceutical companies to research on other PDE inhibitor class. In addition, research on extended use of approved PDE inhibitors is anticipated to benefit the drug in long term and contribute to the increasing revenues of PDE inhibitors market.

• Researchers from the John Hopkin University reviewed the trials of PDE-5 inhibitors in pediatric patients with pulmonary hypertension. The researchers concluded that PDE-5 inhibitors can be safely prescribed to infants, neonates and children with primary and secondary pulmonary hypertension (2017).
• Besides, PDE-5 inhibitor sildenafil accidently developed for treating angina, was also found to be effective in erectile dysfunction and now is observed to benefit heart attack patients. Researchers at Karolinska Institutet, Sweden reported in March 2017 that PDE-5 inhibitors prescribed for erectile dysfunction can lower the risk of death of hospitalization for heart failure in men who have had one heart attack in their lifetime.
• Pfizer, Inc. received FDA approval for its PDE-4 inhibitor Crisaborole (Eucris) in December 2016 for the treatment of mild to moderate atopic dermatitis. Eucrisa the first non-steroidal topical monotherapy for skin disorder.

Many such product developments would be augmenting the global PDE inhibitors market growth in near future.

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New products are primarily targeted in develop economies like North America, Europe and Japan. However, product approval in emerging nations such as India, China, Brazil, Russia, Argentina, and Indonesia would potentially favorable for the market players. Increasing healthcare expenditure and large target population base would support the growth of PDE inhibitors market in these nations. However, market players need to be cautious about uncertain regulatory conditions favoring the economic status and healthcare need of the large patient population.

Some of the key players operating in the global phosphodiesterase enzyme inhibitors market include Pfizer, Inc., AstraZeneca plc, Bayer AG, Eli Lilly & Company, Celgene Corporation, Mist Pharmaceuticals.

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Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.