Safe
and effective drug delivery is a major challenge against the pharmaceutical and
biotechnology companies. Companies formulate their drugs in various dosage
forms such as capsules, powders, inhalers, liquid, drops, tablets, transdermal
patches, depot injection, and gels to address the drug delivery challenges in
different conditions. Moreover, advancement in research has enabled controlled
and sustained release of drugs to decrease the dosage and provide long term
effect of the drug. Furthermore, new technologies such as nanotechnology and
antibody-drug conjugate are being introduced to minimize cost and increase
bioavailability. In all, there is all-together a new wave of innovation in life
science sector that delivers medicines at the targeted site in right dose.
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Nanotechnology-based
platforms are gaining significant importance in research and product
development due to the enormous benefits they offer in terms of drug stability,
bioavailability, dosage, and shelf-life.
Various types of nano-carriers or nanoparticles such as liposomes,
magnetic particle, dendrimers, silver nanoparticle, silica nanoparticle, and
polymeric micelles, carbon nanoparticles and drug-conjugate nanoparticles are
used in different industries to cater the exact need or product.
SiSafe Nano-silicon Drug Delivery Platform
SiSaf’s
new drug delivery technology called SiSafe is a patented elemental nano-silicon
porous structure with a massive surface area. A higher surface area provides
high drug-loading capacity and thus significant increase in bioavailability of
even the most hydrophobic compounds. So, a less soluble drug that needs to be
injected directly in the bloodstream can have enhanced solubility through
SiSafe nano-silicon platform. Molecules are incorporated within the nanopores,
thus stabilizing the instable molecules and increasing the bioavailability of
the drug. SiSafe is a biodegradable technology which enables customizing the
rate of onset and release by altering the physical factors of the carriers such
as linkage method, porosity, particle size, and pore width.
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Potential Applications
SiSafe
will be of significant use to pharmaceutical, animal health, biotech and
cosmeceutical companies to formulate and package drugs that are difficult to
formulate otherwise. Companies finding better solutions for their existing
drugs can incorporate this technology to improve their product quality. Also,
new drugs used for chronic diseases can be delivered at a low dose to the
target sites with the nano-silicon drug delivery platform.
This
new nanotechnology-based drug delivery platform offers competitive advantages
such as improved safety, efficacy, controlled release and desired time of onset
of drug release. After years of research and development, and extensive capital
investment, SiSafe nano-silicon drug delivery platform is ready for commercialization.
SiSaf is looking to partner with drug developers who desire to improve their
formulation with controlled releases and lower doses. SiSaf received a funding
of USD 4.9 million from Singapore’s Vickers Venture Partners and Exen Capital
recently in November 2016. This partnership is anticipated to be of great aid
for SiSaf to reach more markets globally.
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Nano-silicon Drug Delivery Platform to enable Low Cost Drug
Delivery
Research
for the use of nano-silicon particles in targeted tumor therapy is under
progress. The study being conducted by various organizations globally including
Tel Aviv University, Technion – Israel Institute of Technology in collaboration
with Massachusetts Institute of Technology (MIT) and the Harvard Medical School
are of the opinion that nano-silicon particles could deliver drugs over a long
period of time, may be for weeks or even months. Such advancement in drug
delivery technologies will revolutionize the pharmaceutical and
biopharmaceutical drug industry by offering targeted drug therapies at a low
cost.
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meticulously study emerging trends across various industries at both the global
and regional levels to identify new opportunities for our clientele. Our global
team of over 100 research analysts and freelance consultants provide market
intelligence from the very molecular country level and also provide a global
perspective of the market. Our team is of the most vital cog in our robust
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