An
excipient is an inactive substance formulated with the active
ingredient of a medication for the purpose of bulking-up Route of
Administration that contain potent active ingredients. These
substances improve bulkiness and dissolution rate of the drug and are
crucial in drug delivery within the body. A sugar-based excipient is
required if the conventional tablet contains a bitter drug substance
or, more importantly, if the tablet is chewable. Sweeteners are added
in tablets to impart sweetness to the drugs. Sucrose is the standard
against, which all sweeteners, both artificial and natural, are
measured. Apart from being sweeter than sucrose, artificial
sweeteners have the advantage of not disturbing blood sugar levels of
pre-diabetic or diabetic patients, and they are considered to be
non-cariogenic. Sugar-based excipients are widely used as ingredients
in pharmaceutical tableting. They are used for taste masking of
bitter drugs and as bulking agents. Dextrose, fructose, mannitol,
sorbitol, and xylitol are few examples of sugar-based excipients that
are mainly used.
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Sugar-based
Excipients Market Dynamics
Increasing
use of co-processed excipients and rising development of orally
disintegrating tablets (ODTs) are major factors that are expected to
boost growth of sugar-based excipients market over the forecast
period. ODTs are solid dosage forms containing medicinal substances,
which disintegrate rapidly, generally in few seconds, when placed on
the tongue. Research on delivering biological molecules through the
oral route have widened the scope of ODT technology, which further
drive growth of the market. According to the American Pharmaceutical
Review 2016, over 35 products have been launched using Zydis ODT
technology in over 60 countries worldwide. Furthermore, rising use of
sugar alcohols such as mannitol in a wide range of oral dosage and
high adaptability in formulation technologies such as ODTs are
expected to drive the sugar-based excipients market growth over the
forecast period. Sugar alcohol is granular and white like sugar, and
is used as a sugar alternative. The sugar alcohols differ in calorie
content and sweetness level. Their sweetness level ranges from 50% to
100% that of sugar.
Sugar-based
Excipients Market Regional Insights
On
the basis of region, the global
sugar-based excipients market is segmented into North
America, Latin America, Europe, Asia Pacific, Middle East, and
Africa. North America sugar-based excipients market is expected to
hold a dominant position over the forecast period, owing to increased
usage for generic drugs in the region. Increasing investments in drug
development and rising production of generic drugs will drive growth
of sugar-based excipient market in Europe. Significant growth in the
healthcare and pharmaceutical industry, favorable government
policies, low-cost manufacturing, and increasing demand for generic
drugs, especially in emerging economies directly contributes to the
market growth. According to the Food and Drug Administration (FDA)
data, in 2017, Indian firms received around 40% of the new U.S.
approvals for generics with a wider base of companies.
Sugar-based
Excipients Market Competitive Landscape
Some
of the key players operating in the global sugar-based excipients
market include Ashland Inc., Associated British Foods Plc, BASF SE,
Colorcon, Inc., Cargill, Inc., DFE Pharma, FMC Corporation, MEGGLE
AG, Roquette Group, and The Lubrizol Corporation.
Sugar-based
Excipients Market Taxonomy
On
the basis of product, the sugar-based excipients market is segmented
into:
-
Actual Sugars
-
Artificial Sweeteners
-
Sugar Alcohols
On
the basis of excipient type, the sugar-based excipients market is
segmented into:
-
Crystals
-
Direct Compression Sugars
-
Powders/granules
-
Syrups
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