Key
players in the market are engaged in extensive research and
development to launch new targeted cell therapies in the market. For
instance, the University of Texas MD Anderson Cancer Center, Houston
is conducting phase 1 clinical trial studies of central
memory–derived CD19 CAR T–cell therapy for relapsed
intermediate-grade B-cell non-Hodgkin lymphoma. Moreover, key players
are focusing on strategic merger and acquisition to enhance their
share in the global CAR-T cell therapy market. For instance, in April
2018, Pfizer, Inc. signed a deal with Allogene, to develop an
investigational CAR-T cell therapy for treating cancer.
Key
players operating in the global CAR-T cell therapy market include
Novartis International AG, Kite Pharma, Inc. (Gilead Sciences, Inc.),
Juno Therapeutics (Celgene Corporation), Bluebird Bio, Inc. (Celgene
Corporation), Sorrento Therapeutics Inc., Mustang Bio, Inc., Aurora
Biopharma Inc., Legend Biotech (Genscript Biotech Corporation),
Pfizer, Inc., CARsgen Therapeutics, Ltd., and others.
CAR-T
cell therapy is expected to be an important development in cancer
treatment and therapeutics industry due to its cost efficiency.
Moreover, rising incidence of cancer is leading to high demand for
its treatment.
According
to the World Cancer Research Fund International (WCRFI), around 14.1
million cancer cases were reported worldwide, in 2012. As per WCRFI,
it is projected that by 2035, around 24 million cancer cases would be
observed worldwide.
Moreover,
introduction of new therapies into the market is further expected to
bolster growth of CAR-T cell therapy market. For instance, in October
2017, the U.S. Food and Drug Administration granted marketing
approval to Yescarta (axicabtagene ciloleucel), a cell-based gene
therapy, to treat adult patients with certain types of large B-cell
lymphoma.
CAR
T cell therapy market is expected to be primarily driven by
increasing demand for highly effective therapy mode of treating
cancer. Combating cancer has been a major concern for healthcare
industry for years.
CAR
T cell works on gene transfer technology that boosts the immune
response of cancer affected individual by destroying affected tumor
cells. It has been analyzed to act as a lifesaving drug for over 30
million patients’ sufferings from lymphoma. Though the CAR T cell
therapy market outlook is highly optimistic, market players need to
address the manufacturing and scalability options to generate higher
profits. Novartis and Kite have already started building a roadmap
for it.
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