Global Label-Free Array Systems
Market Regional Analysis
North America is expected to hold
dominant position in the global Label-Free
Array Systems Market over the forecast period, owing to the wide spread
presence of the key manufacturers in the North American. For instance, General
Electric, Reichert, Inc., NanoSPR Devices, Bruker Corporation, and others are
some of the key manufacturers, which have their presence in the North America
region.
Moreover, many acquisitions have
taken place in the recent past in the global label-free array systems market
for the development and introduction of new products. For instance, in 2018,
Bruker Corporation acquired Sierra Sensors GmbH, a manufacturer of innovative
analytical biosensors-based on SPR detection. Sierra Sensors GmbH have the
technology to measure the specificity, affinity, thermodynamics and kinetic
rates of interaction between molecules, while Bruker Corporation have the
facilities for mass spectrometry, nuclear magnetic resonance (NMR) and X-ray
crystallography. Both the technologies can be combined efficiently for the
development in drug discovery process. The above factors are expected to boost
the global label-free array systems market growth over the forecast period.
Label-free array systems tools have
many applications such as drug development, diagnostics etc. Label-free array
systems comprises two types of biosensors such as optical biosensors and
impedance-based biosensors, which involves techniques such as surface plasmon
resonance (SPR), isothermal titration calorimetry (ITC), bio-layer
interferometry, and others. Moreover, SPR is the most commonly used technique.
Many key players manufacture modified versions of SPR, which are marketed along
with the SPR accessories and consumables. For instance, General Electric
Healthcare, manufactures Biacore T200, a versatile instrument for high quality
characterization of molecular interactions, where interactions from ions to
viruses can be evaluated.
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Moreover, General Electric also
manufactures and markets SPR consumables such as sensor chip, running buffers,
regeneration solution, capture reagents, and others. Some other manufacturers
operating in the global label-free array systems market include General Electric,
BioNavis Ltd, and others.
Global Label-Free Array Systems
Market Drivers
Increasing adoption of label-free
array systems in the drug discovery process is expected to drive the global
label-free array systems market growth over the forecast period. For instance,
according to the National center for Biotechnology Information, (NCBI), 2016,
label-free array systems are extensively used for secondary screening to find
the lead molecule for the drug development process from the small molecule hits
and it is also used for lead optimization to find the candidate drug from the
leads molecules. Moreover, according to the same source, currently the
label-free array systems are extensively used for evaluating kinetics between
the drug molecule and its receptor, as it is most important bond that is characterized
for drug discovery process.
Leading manufacturers are focused
on manufacturing new products in the global label-free array systems market
over the forecast period. For instance, in 2018, Bruker Corporation launched a
modified version of SPR, Sierra SPR-32 system, with higher sensitivity,
modified instrument control software to enable highest SPR throughput with
outstanding sensitivity. These factors are expected to drive the global
label-free array systems market growth over the forecast period.
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Global Label-Free Array Systems
Market Restraints
Lack of skilled persons to
perform label-free techniques in developed as well as in the emerging economies
is expected to hamper growth of the global label-free array systems market over
the forecast period. The protocols used in the techniques are very specific and
requires a trained person to carry out the procedure. The procedure should be
carried out with higher precision and less errors.
Moreover, SPR products are very
expensive and this is expected to hinder the growth the market. For instance,
cost of imaging systems offered by Biacore (acquired by GE Healthcare) range
between US$ 200,000 and US$ 300,000. Moreover, reagents supporting such systems
are very costly, which increases the overall cost per interaction. These
factors are expected to restrain the global label-free array systems market growth
over the forecast period.
Global Label-Free Array Systems
Market Key Players
Some of the key manufacturers
operating in the global label-free array systems market include General
Electric Healthcare, BioNavis Ltd, Reichert, Inc., Metrohm India Limited,
Horiba instruments Incorporated, ABL&E Group, plasmetrix.com, Nicoya,
NanoSPR Devices, Biosensing Instrument, and Bruker Corporation.
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