Digital PCR and Real-time PCR
(qPCR) Market: Regional Analysis
North America is expected to hold
dominant position in the Digital
PCR and Real-Time PCR Market, owing to increasing number of cancer cases,
favoring the demand for PCR diagnostic tools and assays. According to a
National Cancer Institute, 2016, an estimated 1,735,350 million new cases of
cancer will be diagnosed in the U.S., with around 609,640 deaths from the
disease in 2018. The number of people suffering from cancer is expected to rise
to 19 million by 2024.
Polymer chain reaction (PCR)
creates unlimited copies of DNA from a single strand using polymerase enzymes,
primers, and multiple thermal cycles. PCR diagnostics are less prone to
cross-contamination, as the procedure is conducted in automated thermal
cyclers. dPCR and qPCR are common diagnostic techniques used in the research,
pharma, and biotech institutes, and are widely used in variety of applications.
Real-time PCR allows specific and
early disease diagnosis, allowing speedy and selective treatment for the
patient. Also, PCR techniques have replaced the conventional infectious disease
detection methods such as immunoassays as they are more specific and have
become an integral part of laboratory diagnosis, thereby facilitating market
growth.
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Digital PCR and Real-time PCR
(qPCR) Market: Dynamics
Increasing adoption of qPCR in
medical diagnosis to detect RNA viruses such as HIV and hepatitis C is expected
to propel the market growth. According to the International Journal of
Nanomedicine, 2017, around 36.7 million people were affected by human
immunodeficiency virus (HIV) and around 400 million people were affected with
viral hepatitis, globally. The survey also stated that with no reliable
treatment for HIV infection, early diagnosis is a critical factor in managing
AIDS patients, as it is a major cause for morbidity and mortality, globally.
Moreover, launch of
technologically advanced products is expected to enhance the market growth. For
instance, in November 2013, GNA Biosolutions GmbH launched an ultrafast PCR
platform, Pharos V8 platform based on laser PCR. The platform uses nanomaterial
to accelerate PCR reaction, by a factor of ten, thus making it suitable to be used
in time-sensitive settings.
However, high device cost and
adoption of alternative assays for disease detection and analysis is expected
to hinder the market growth.
Digital PCR and Real-time PCR
(qPCR) Market: Key Players
Key players operating in the
global digital PCR and real-time PCR market include Thermo Fisher Scientific,
Inc., Bio-Rad Laboratories, Inc., Abbott Laboratories, F. Hoffmann-La Roche
Ltd., Qiagen N.V., Takara Bio, Inc., Danaher Corporation, Merck KGaA, Becton,
Dickinson and Company, and Agilent Technologies, Inc.
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Key development
In April 2019, Thermo Fisher
Scientific Inc. introduced Applied Biosystems QuantStudio 6 and 7 Pro Real-Time
PCR Systems, which includes new specifications like facial authentication,
voice command and radiofrequency identification.
In January 2019, QIAGEN N.V.
announced the development of range of next-generation systems for the digital
polymerase chain reaction (digital PCR or dPCR) one of the fastest-growing
molecular testing applications, which is expected to launch in 2020.
In 2017, Bio-Rad Laboratories,
Inc. introduced iQ-Check Enterobacteriaceae real-time PCR detection kit that
can be used for 94 samples.
In 2017, Agilent Technologies
Inc. launched AriaDx Real-Time PCR System for Clinical Diagnostics in Europe to
expand its molecular diagnostic portfolio.
In 2016, Danaher Corporation
acquired Cepheid Inc. to expand its qPCR-product portfolio.
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