The global P2X7
receptor antagonists market, by Drugs (AKP-23494954/RQ-00466479, EVT 401,
GSK1482160, JNJ-55308942, JNJ-54175446, and Others (e.g.- AZ11657312)), by
Application (Central Nervous System Disorders, Immunological Disorders, and
Others), and by Region (North America, Latin America, Europe, Asia Pacific,
Middle East, and Africa), is expected to be valued at US$ 96.6 million in 2024,
and is projected to exhibit a CAGR of 18.3% over the forecast period (2024–
2026).
P2X7 receptor antagonists of
Johnson & Johnson are considered while estimating the size of the global
P2X7 receptor antagonist market over the period 2024 to 2026. Currently only
two companies’ molecules are in phase 1 trials in the U.S. i.e. Johnson &
Johnson, and GlaxoSmithKline. JNJ-55308942 (Johnson & Johnson) is in Phase
1 clinical trials and is indicated for the treatment of mood disorders. Study
start date for JNJ-55308942 was March 15, 2018, and ended on October 19, 2018.
Another drug, JNJ-54175446 (Johnson & Johnson, study started on March 24,
2017, and ended on November 14, 2017) is also in Phase 1 clinical trials
indicated for the treatment of a major depressive disorder. It is assumed that
Johnson & Johnson will complete clinical trials in 2023 and will be able to
launch the products in the market in the year 2024, as various phase 1 studies
have been conducted for Johnson & Johnson drugs which would boost global
P2X7 receptor antagonist market growth. These factors are expected to support
global P2X7 receptor antagonist market growth over the forecast period.
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Browse 16 Market Data Tables and
14 Figures spread through 94 Pages and in-depth TOC on Global P2X7 Receptor
Antagonists Market, by Drugs (AKP-23494954/RQ-00466479, EVT 401, GSK1482160,
JNJ-55308942, JNJ-54175446, and Others (e.g.- AZ11657312)), by Application
(Central Nervous System Disorders, Immunological Disorders, and Others), and by
Region (North America, Latin America, Europe, Asia Pacific, Middle East, and
Africa) - Global Forecast to 2026
In March 2018, Asahi Kasei Pharma
Corporation and RaQualia Pharma Inc. entered into a license agreement for a
novel P2X7 receptor antagonist. Under this agreement, Asahi Kasei Pharma
obtained exclusive rights for worldwide development, manufacture, and sale of
P2X7 receptor antagonist, while RaQualia Pharma will receive a lump-sum payment
as well as milestone payments corresponding to stages of development, and
royalty payments in proportion to sales amounts. The P2X7 antagonist is
AKP-23494954/RQ-00466479. In 2016, CONBA Pharmaceutical revised the synthetic
route for EVT401. Furthermore, additional pre-clinical pharmacokinetics and
safety studies are being conducted in order to meet the requirements of the
China Food and Drug Administration prior to seeking approval for further
clinical studies. In 2012, Evotec AG granted exclusive rights for EVT401 in
China to CONBA Pharmaceutical. These factors are expected to support global
P2X7 receptor antagonist market growth over the forecast period.
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Key Takeaways of the Global P2X7
Receptor Antagonists Market:
The global P2X7 receptor
antagonists market is expected to exhibit a CAGR of 3% over the forecast
period. This is owing to launch of P2X7 receptor antagonists late in the
forecast period
Manufacturers are working towards
development of P2X7 receptor antagonists and expect to launch these over the
forecast period supporting global P2X7 receptor market growth over the forecast
period
North America is expected to hold
a dominant position in the global P2X7 receptor antagonists market over the
forecast period, owing to product launches and potential customer base
Major players operating in the
global P2X7 receptor antagonists market include, GlaxoSmithKline Plc, Johnson
& Johnson, AstraZeneca Plc, RaQualia Pharma, Evotec AG, and Asahi Kasei
Corporation
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