Surface plasmon resonance (SPR)
is used to detect the interaction of two different molecules in which one is
mobile and one is fixed on a thin gold film and to study molecular
interactions. The technology finds application in drug discovery, material
science, and biosensors.
The global Surface
Plasmon Resonance Market is estimated to account for US$ 1,244.7 Mn in terms
of value by the end of 2027.
Global Surface Plasmon Resonance
Market: Drivers
Increasing use of SPR in analysis
of biomolecular interactions between protein-protein, protein-DNA,
enzyme-substrate or inhibitor, receptor-drug, lipid membrane-protein, and cell
or virus proteins is expected to propel growth of the global surface plasmon
resonance market over the forecast period. SPR technique is considered as the
gold standard for real time, label-free measurements of biomolecules, owing to
various advantages such as time-saving and high reliability. It also offers
real time monitoring, reusable sensor chips, flexible experimental design, and
reproducible measurements.
Global Surface Plasmon Resonance
Market: Opportunities
Increasing R&D in
miniaturization and cost reduction of products related to SPR technique is
expected to offer lucrative growth opportunities for players in the market.
Localized SPR (LSPR) sensors possess a smaller footprint and are more
cost‐effective. Moreover, these sensors demonstrate higher sensitivity to small
variations of the refractive index compared to conventional SPR metallic thin
film sensors. For instance, in January 2020, researchers from University of
Coimbra, Portugal, reported assessment of optical properties of Au‐WO3
nanocomposite coatings for LSPR sensing.
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Global Surface Plasmon Resonance
Market: Restraints
Temperature fluctuations in an
SPR-based system affect the final outcome as these fluctuations change the
ratio of association rate to dissociation rate and affects rate of efficiency
of binding events. This in turn is expected to lower the adoption of SPR, which
is expected to hamper growth of the market.
Key Takeaways:
The Material Science segment in
the global surface plasmon resonance market was valued at US$ 73.8 Mn in 2019
and is expected to reach US$ 102.3 Mn by 2027 at a CAGR of 5.1% during the forecast
period. The growth of the segment is attributed to increasing use of Surface
Plasmon Resonance in pharmaceutical industry.
The Imaging System segment held
dominant position in the global surface plasmon resonance market in 2019,
accounting for 56.4% share in terms of value, followed by reagents segment,
respectively. The dominance of imaging system segment is attributed to
increasing research to study drug cell interaction for development of new drug
product.
Market Trends
The global surface plasmon
resonance market is witnessing increasing adoption of label-free detection
technique for analysis of biomolecules in order to reduce the assay cost and
complexity while providing more qualitative information through labelled
detection. In label-free detection, a sensor functions as a transducer to
convert one of the physical properties of the analyte into a quantifiable
signal. Specific instruments are later used to analyze the signal. A transducer
can measure the physical property of the molecule. Moreover, label-free
detection technique reduces the time and efforts required for the development
of assay and thus simplifies the procedure.
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The demand for LSPR-based
biosensor is increasing for rapid detection of biomolecules and in diagnostic
and point-of-care testing (POCT) applications. This can be attributed to the
interactions of biomolecules and sensing surface during the progression of
LSPR. The demand for LSPR-based techniques for real-time cell monitoring
applications as these techniques do not require any multiple fluorescence
staining procedures or secondary antibodies.
Global Surface Plasmon Resonance
Market: Competitive Landscape
Major players operating in the
global surface plasmon resonance market include, Bio-Rad Laboratories, Inc.,
Carterra Inc., General Electric Co., AMETEK, Inc., Bristol Myers Squibb,
Horiba, Ltd., Bruker, and Biosensing Instrument Inc.
Global Surface Plasmon Resonance
Market: Key Developments
In August 2019, Carterra Inc.
started a Customer Experience Center (CEC) and office in Munich, Germany, owing
to rapid adoption of Carterra’s LSA platform in the European market
In June 2018, Bruker announced
the launch of its new SierraTM SPR-32 system with new instrument control
software to enable high SPR throughput, at the European SLAS 2018 meeting.
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