Diclofenac Patches Market Drivers
Diclofenac
patches market is expected to witness significant growth over the forecast
period, owing to high prevalence of chronic pain disease. According to the
American Academy of Pain Medicine (AAPM), in 2011, around 1.8 billion people
suffered from chronic pain. Moreover, the National Institutes of Health (NIH)
estimates that one in 10 people in the U.S. suffer from chronic pain. According
to a study published in the British Medical Journal in 2016, nearly one-third
to half of the population in the U.K. suffers from chronic pain. Moreover,
according to the NIH estimates published in 2015 by the American Pain Society
(APS), around 50 million people in the U.S. suffered from chronic pain.
Moreover, rising prevalence of pain and increasing prevalence of diseases such
as cancer and others are driving the diclofenac patches market growth. For
instance, according to the National Cancer Institute, in 2018, around 1,735,350
new cases of cancer are expected to be diagnosed in the U.S. and 609,640 people
are expected to die from the disease. Furthermore, according to the Cancer
Atlas: 2017, there were an estimated 14.1 million new cancer cases in 2012.
Moreover, India, China and other East and Central Asian countries accounted for
nearly half of world’s new cancer cases and deaths, in 2017. In addition,
according to the same source, by 2025, there will be an estimated 19.3 million
new cancer cases and 11.4 million cancer deaths, in less developed regions.
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Diclofenac is nonsteroidal
anti-inflammatory drug (NSAID), which works in reducing hormones that cause
inflammation and pain in the body. Non-steroidal anti-inflammatory drugs
(NSAIDs) are the most widely used therapeutic class of analgesic compounds,
indicated to use in relieving post extraction pain. Diclofenac sodium is a
commonly prescribed NSAID, which exhibits anti-inflammatory, analgesic and
anti-pyretic activity. Diclofenac transdermal patches are used to get temporary
relief of minor aches and pains of the muscle and joints that are applied
directly to the area of pain. Transdermal diclofenac patches are found to be more
effective as compared to the diclofenac tablets, owing to its once-daily
application and lesser frequency of systemic adverse effects. Transdermal
patches have been developed to offer innovative drug delivery system for
diclofenac, with reduced incidence of systemic adverse effects due to lower
plasma concentrations. Diclofenac patches are designed to treat pain associated
with conditions such as gout, migraine, rheumatoid arthritis, sprains of
muscles and joints and in mild to moderate fever in some cases.
Growing research developments in
the NSAIDs to increase its effectiveness pain management and to extend its
application in various areas of medical field, will drive the diclofenac
patches market. For instance, a study published in the International Journal of
Ophthalmology: April 2018, stated that, application of prophylactic
non-steroidal anti-inflammatory drugs (NSAIDs) in pre- and post-cataract
surgery may help to reduce the severity and frequency of the development of
cystoid macular edema (CME) in the eyes of diabetic patients. Furthermore, in
November 2017, researchers at the Indian Institute of Technology (IIT)
Hyderabad have developed a novel skin patch which releases diclofenac at the
target site in a controlled way in such way that, there will be constant
release of the drug for as long as 12 hours. In addition, the drug has low
half-life of one–two hours and therefor constant release for up to 12 hours
offers consistent efficiency of diclofenac for a longer period.
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Diclofenac Patches Market
Restraint
Diclofenac patches shows
increased risk of heart attack or stroke when applied for longer duration than
it prescribed, hindering the growth of diclofenac patches market size. NSAIDs
cause an increased risk of serious cardiovascular thrombotic events, including
myocardial infarction (MI) and stroke, which can be fatal. This risk may occur
early in treatment and may increase with duration of use. Diclofenac patches
also associated with major to minor side effects including abnormal pain,
constipation, nausea and vomiting, skin rash and tinnitus.
Furthermore, an acceptance of
diclofenac patch in the routine practice are low, compared to the diclofenac
tablet or injection, which is probably due to the lack of awareness and a
mental inertia to accept a new concept among the medical professionals and
patients.
Diclofenac Patches Market -
Regional Analysis
On the basis of region, global
diclofenac patches market is segmented into North America, Latin America,
Europe, Middle East, Asia Pacific, and Africa. North America holds dominant
position in diclofenac patches market, owing to the higher prevalence of
strains, sprains of muscle and joints, in this region. According to the
National Health Statistics Reports: November 2016, there were an estimated
4,262 numbers of sprains and strains injury are reported in the U.S. between
2011 and 2014, which is also the major cause (41.4%) of natural injury in
sports and recreation-related injury episodes.
Diclofenac Patches Market –
Competitive Landscape
Key players operating in the diclofenac
patches market include Pfizer Inc., Cadila Healthcare, GlaxoSmithKline
Pharmaceuticals Ltd., Hisamitsu Pharmaceutical co. Inc. and Teikoku Seiyaku
Co., Ltd.
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