Market Player
The global Dermal
Regeneration Template Market has only one FDA approved product from Integra
LifeScience. The growing research related to innovation in material and design
is expected to penetrate many companies in the market. In 2016, a research
funded by Welcome Trust described a novel approach to increase the thickness of
elastic- layered fiber for geriatric patients and created a hybrid of Integra
dermal regeneration template.
Dermal regeneration template
market
Dermal regeneration template is a
two-layered skin regeneration system. The outer layer of dermal regeneration
template is made of thin silicone film act as the epidermis of skin. The outer
layer of dermal regeneration template helps in protecting wound from infection
and controls in loss of both heat and moisture. The outer collagen
Glycosaminoglycan (GAG) thermal layer functions as a biodegradable template
that helps in regeneration of dermal tissue neodermis by the body. The inner
layer of dermal regeneration template is made of complex matrix of cross-linked
fibers. The porous material of the template helps in regeneration of skin. The
cross-linked fiber material of dermal regeneration template acts a scaffold for
the re-growth of skin layer. Once the dermal skin layer is regenerated the
outer layer of template is removed and is replaced with a thin epidermal skin
graft. This procedure leaves the wound to a flexible, growing and allows
permanent regeneration of skin. It allows faster healing of wound with minimum
scarring. Using dermal regeneration template allows immediate wound closure
without risking any loss of donor material. In 2005, Integra LifeSciences
received FDA approval for its INTEGRA Dermal Regeneration Template as a
treatment for life-threatening burn injuries and reconstructive surgery for the
repair of scars when other therapies fail. Recently, In January 2016, Integra
LifeSciences received FDA approval for treatment of Chronic Diabetic Foot
Ulcers (DFU) with dermal regeneration template. The application of this
template is typically completed in two operative sessions involving the product
applied to the excision sites and the second procedure performed 3 to 6 weeks
after the placement of product to remove silicone layer and for an epidermal
autograft applied to the neodermis.
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Future Market Outlook for Dermal Regeneration Template
Market
The global dermal regeneration template market is expected
to witness significant growth due to increase in incidence of burn injuries and
prevalence of diabetes globally. As per the report of WHO in 2016, burns result
in around 265,000 deaths every year. Low income and middle income countries
contribute majority to the total number of burns every year. In India alone,
over 1,000,000 people suffer from moderate to severe burns each year. In
Bangladesh, Egypt, Columbia and Pakistan, around 17% of children with burn have
temporary disability where as 18% have permanent disability. The increasing
cases of burns and awareness among the population of low and middle income
countries provides opportunity for dermal regeneration template industry. The
growing concern with burning cases and governments initiatives to grow
awareness among patients related to burn treatment through campaigns and
national burn Awareness week to act as a fuel to the growth of dermal
regeneration template market. In 2010, the U.S. Department of Health &
Human Services initiated medical countermeasures (MCMs) program, aimed to
improve burn treatment for mass causality. The increasing research fund and
grants associated for burn research is creating opportunity for dermal
regeneration template manufacturers to come up with products with more
innovations. American burn association (ABA) is one of such organization of the
U.S. that offers awards, grants and fellowship opportunities to practitioners
for education, prevention and rehabilitation of burn. The growing usage of skin
grafts and skin replacement substitutes are expected to act as a restrain to
the global dermal regeneration market. Dermal regeneration template usage in
chemical, radiation or electrical burns are limited and can only be used after
thorough evaluation by surgeon. The product can be only used in excision
therapy and are contraindicated for infectional wounds. Their limitation for
incision use and usage in chemical and radiation is expected to hamper the
overall growth. North America, Europe and Asia Pacific contribute major revenue
to the overall market. Asia Pacific is expected to grow with high CAGR as
compared to other region.
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Key Developments
Increasing product development and launches by Integra
LifeSciences are expected to aid growth of the global dermal regeneration
template market. For instance, in May 2017, Integra LifeSciences Holdings
Corporation announced the European launch of its Integra Dermal Regeneration
Template (IDRT) Single Layer ‘Thin’, which is an extension of the company’s
collagen range of dermal repair products.
Moreover, Integra LifeSciences is also focused on strategic
acquisitions in order to expand its product portfolio and revenue. In July
2019, the company announced the acquisition of Arkis Biosciences Inc., a
privately-owned company which offers a strong portfolio of neurosurgical
devices.
Similarly, the life sciences company is engaged in obtaining
strategic investments and funding to strengthen its market position. In August
2019, it was announced that ARP Americas LP invested US$ 302,000 in Integra
Lifesciences Holdings Corp. These investments are expected to help the
company’s develop, manufacture, and market its surgical implants and medical
instruments that have application in neurosurgery, extremity reconstruction,
orthopedics, and general surgery.
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