Immune
repertoire sequencing is extensively used in biomarker discovery to
improve the success rate and cost-effectiveness of rational drug
development. For instance, in November, 2017, the Center for
Commercialization of Cancer Immunotherapy (C3i) started offering T
cell receptor-beta sequencing services in its Biomarker and
Diagnostic unit in Canada. Increasing demand for personalized
medicine, in turn, is expected to aid the immune repertoire
sequencing market growth, as personalized medicine uses an
individual’s genetic profile to guide decisions made in regard to
the diagnosis, prevention, and treatment of diseases.
The
global immune repertoire sequencing market size was valued at US$
114.3 million in 2017, and is expected to witness a CAGR of 5.6% over
the forecast period (2018 – 2026).
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Increasing
Research & Development and Demand for Genomic and Repertoire
Sequencing-based Research is expected to Drive Growth of the Immune
Repertoire Sequencing Market
Increasing
research and development and launches of novel products by key
players are expected to be the major driving force for global immune
repertoire sequencing market growth in the near future. For instance,
in 2016, ArcherDX, Inc. expanded its product portfolio with the
launch of Archer Immunoverse immune repertoire sequencing assays at
the American Society of Hematology (ASH). In 2017, ArcherDX, Inc.
launched Archer Immunoverse B Cell Receptor (BCR) assays to
characterize the human B cell repertoire.
According
to a study published by Cold Spring Harbor Laboratory, in 2017,
researchers from Stanford University applied immune repertoire
sequencing to identify disease-related signatures in the immune
systems of patients with systemic sclerosis-related pulmonary
hypertension (SSc-PAH), a rare chronic autoimmune disease that
affects the connective tissue. Therefore, increasing research on
immune repertoire sequencing is expected to create a favorable
environment for immune repertoire sequencing market growth in the
near future.
Immune
Repertoire Sequencing Market - Regional Insights
On
the basis of region, the global immune repertoire sequencing market
is segmented into North America, Latin America, Europe, Asia Pacific,
Middle East, and Africa. North America is expected to hold a dominant
position in the global immune repertoire sequencing market during the
forecast period, owing to high presence of key industry players in
the region (including Illumina Inc., Thermo Fisher Scientific,
Pacific Biosciences, and CD Genomics). These players are increasingly
focusing on development of novel technologies for immune repertoire
sequencing. For instance, in 2017, 10x Genomics Inc., U.S. based
company, added B-Cell and 5’Unbiased Enrichment Kit to its chromium
immune repertoire profiling solution or immune repertoire sequencing.
Immune
Repertoire Sequencing Market - Competitive Landscape
Key
players operating in the global immune repertoire sequencing market
include Thermo Fisher Scientific, Inc., Illumina Inc., ArcherDX,
Inc., Roche Holding AG, Pacific Biosciences, CD Genomics, Atreca,
Inc., Adaptive Biotechnologies, Oxford Nanopore Technologies, Ltd.,
Qiagen N.V., Agilent Technologies, Inc., and Takara Bio, Inc.
Detailed
Segmentation:
Global
Immune Repertoire Sequencing Market, By Product Type:
-
Assay Kits
-
T-Cell Receptor (TCR) Kits
-
B-Cell Receptor (BCR) Kits
-
Instruments
Global
Immune Repertoire Sequencing Market, By Application:
-
Cancer Immunotherapy
-
Biomarker Discovery
-
Autoimmune Diseases
-
Vaccine Development and Efficacy
-
Transplant Rejection and Tolerance
-
Infectious Diseases
-
Other Applications
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