Optogenetics
Actuators & Sensors Market by Actuators (Channelrhodopsin,
Halorhodopsin, and Archaerhodopsin), by Sensors (Genetically Encoded Calcium
Indicators, Voltage-Sensitive Fluorescent Proteins, and pH Sensors), by Devices
(Light Emitting Diode, Lasers, and Others), by Application (Retina related
disorder, Neural disorder, Psychological disorder and Others) and by Geography
(North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) -
Size, Share, Outlook, and Opportunity Analysis, 2018 – 2026
Optogenetics is the technique in
which optically-activated proteins are used to control neuronal function. It is
one of the recent development in neuroscience, which provides treatment options
to incurable disease such as retinal diseases, Parkinson’s, and Alzheimer’s
disease. Optogenetic techniques allow activation or inhibition of the specific
neurons with a high degree of spatial, temporal, and neurochemical precision.
In this technique, gene which code for light sensitive protein is taken out of
algae species. This protein is actually act as ion channel that opens or close
in response to specific wavelength of light. The gene which code for this
protein is inserted into specific neuron in the brain and it express to produce
this light sensitive protein. On flashing light on specific neural cell, there
is conduction of the neural signal. This technique can be utilized to control
movement of neuron and to understand functioning of brain cells at cellular
level.
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Optogenetics Actuators & Sensors
Market - Market Dynamics
Factors responsible for growth of
the optogenetics actuators & sensors market are rise in burden of retinal
disease and neurological disorders, rapid development and research in the field
of optogenetics, and government initiatives such as funding support for
development of this field. Optogenetics allow to understand which biochemical
and physiological pathway is working for cause of particular disease, which may
help to find treatment for particular disease by flashing blue light on
specific neural cells. According to World Health Organization’s factsheet in
2016, age-related macular degeneration (AMD) ranked third among the global
causes of visual impairment with a blindness prevalence of 8.7 %. Age-related
macular degeneration is the primary cause of visual deficiency in
industrialized countries. Alzheimer’s disease is another potential area in
which optogenetics could give sustainable treatment solution. According to
World Alzheimer Report in 2016, there were an estimated 46.5 million
Alzheimer’s disease patients across the world. Moreover, every three second,
one new case of Alzheimer’s disease is registered, worldwide.
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Optogenetics Actuators & Sensors
Market - Regional Insights
On the basis of geography,
optogenetics actuators & sensors market is segmented into North America,
Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is
expected to be the dominant region in the optogenetics actuators & sensors
market. Most of the optogenetics related research is ongoing in the U.S., which
is why it serves as a conducive environment for growth of the market. There is
strong government funding to carry research and development in this field as
optogenetics has potential to better understand pathophysiology in chronic
neural disease such as Alzheimer’s disease and Parkinson’s disease, which has
high prevalence rate in the U.S. National Institute of Mental Health of the
National Institutes of Health (NIH) in 2016, awarded grant of US$ 1.4 million
to Max Planck Florida Institute for Neuroscience and NYU Langone Medical Center
for research in optogenetics. Companies such as GenSight Biologics have its
optogenetics research platform GS030 in preclinical stage.
Optogenetics Actuators &
Sensors Market - Competitive Landscape
Key players present in the
optogenetics actuators & sensors market are Bruker, Circuit Therapeutics,
Inc., Gensight Biologics, AGTC, Prizmatix, Merck KGaA, Elliot Scientific Ltd.,
Coherent, Inc., The Jackson Laboratory, Scientifica (Judges Scientific Plc
Company), Addgene, Shanghai Laser & Optics Century Co., Ltd. (SLOC), Noldus
Information Technology, Thorlabs, Inc., and Danaher.
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