Immunoglobulins
are critical part of the immune response, which specifically
recognize and bind to particular antigens such as bacteria or viruses
aiding in their inhibition. Immunoglobulins also called as antibodies
are the glycoprotein molecules produced by plasma cells i.e. white
blood cells. The antibody immune response is highly complex and very
specific. The various immunoglobulin classes and subclasses
(isotypes) differ in their biological features, structure, target
specificity and distribution. Hence, the assessment of the
immunoglobulin isotype can provide useful insight into complex
humoral immune response. There are different classes of
immunoglobulin such as IgG, IgA, and IgM, which are used for the
treatment of various immunological and neurological diseases. These
immunoglobulins can be administered intravenously and subcutaneously.
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Immunoglobulin Market Dynamics
Furthermore,
increasing application of immunoglobulin
is gaining significant traction among pharmaceutical and
Biopharmaceuticals Company for the research and development of
immunoglobulin. Moreover, increasing number of intravenous product
approvals and clinical trials for new clinical applications is
anticipated to provide potential growth opportunities to the
industry. For instance, in May 2018, ADMA Biologics, Inc. announced
that the company had received U.S. patent for treating respiratory
infection. The patent consist of usage of polyclonal immunoglobulin
preparation for treatment of respiratory infection, where the issued
patent extends to January 2035.
Kedrioin Biopharma and Kamada Ltd. together in May 2018, launched two
human-derived protein therapeutics companies announced that KEDRAB
[Rabies Immune Globulin (Human)] has been launched in the U.S. as it
has received U.S. Food and Drug Administration approval for passive,
transient post-exposure prophylaxis of rabies infection, when given
immediately after contact with a rabid or possibly rabid animal and
concurrent with the rabies vaccine. Such advancement and launches in
field of immunoglobulin are expected to foster growth of the
immunoglobulin market in near future.
Immunoglobulin Market - Regional Insights
Geographically, global Immunoglobulin market is segmented into North
America, Latin America, Europe, Asia Pacific, Middle East, and
Africa. North America accounted for the largest share in the
immunoglobulin market, followed by Europe in 2016. This is attributed
to increasing number of the U.S. Food and Drug Administration
approval for immunoglobulin. For instance, in 2016, Shire plc.
announced the launch of CUVITRU [Immune Globulin Subcutaneous
(Human), 20% Solution] the first and only Subcutaneous 20% treatment
option without proline available in the U.S. to treat adult and
pediatric patients (two years of age and older) with primary
immunodeficiency (PI).
Immunoglobulin Market - Competitive Analysis
The major players operating in the market include Baxter
international Inc., CSL Ltd., Grifols S.A, Octapharma AG, Kedrion
Biopharma Inc., LFB group, Biotest AG, China Biologics Products,
Inc., BDI Pharma Inc., and Bayer Healthcare. Other players in the
immunoglobulin market include Hualan Biological Engineering Inc.,
Omrix Biopharmaceuticals Ltd., Behring GmbH, Shanghai RAAS Blood
Products Co., Ltd., Option Care Enterprises, Inc., ADMA Biologics,
Inc., and BioScrip, Inc.
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