Chronic
diseases often lead to catastrophic damage to vital organs. This
damage is usually irreversible and leads to lifetime dependency on
medicines. Under such severe conditions, transplants remain the
mainstay for restoration of healthy life. Globally, there has been a
surge in tissue transplant with advances in medical biotechnology.
Tissue
transplantation and services market
has seen an increased demand especially from high income countries.
Higher prevalence of diseases such as diabetes, cancer,
cardiovascular diseases, renal diseases and Alzheimer’s disease
have post a threat of irreversible tissue damage to a large
population globally. According to an article published in the Journal
of Diabetes Care, in 2010, prevalence of diabetes related end stage
renal disease escalated from 17,727 in 1990 to 48,215 in 2006 in the
U.S. Large percentage of cancer patients need to undergo bone marrow
transplant. Bone marrow and peripheral blood stem cell
transplantation procedures are essential in restoration of stem cells
that have been destroyed due to high doses of chemotherapy and
radiation treatment. According to World Health Organization,
globally, over 14 million new cases and 8.2 million cancer related
deaths were recorded in 2012. Thus, a large target population base
exists for companies in the global tissue transplantation products
and services market.
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Global Tissue Transplantation Market Segment:
Based on the Tissue Type:
• Cornea
• Heart Valve
• Skin Grafts
• Vascular Grafts
• Bone Marrow
• Bone Grafts
Based on the Tissue Geography:
• North America
• Europe
• Asia Pacific
• Latin America
• Middle East
• Africa
Tissue transplantation products mainly include processed stem cells,
which involve multiplication and differentiation as per patient
requirements. Government standards and guidelines have been set for
storage and processing of stem cells for therapeutic purposes. Some
of the government as well as private service providers include NHS
Blood and Transplant, Tissue Services, U.K., LifeCell Corporation,
Mid-America Transplant Services, Australian Red Cross Blood Service.
These institutes provide storage and processing services to
transplant patients. Bone marrow storage banks have been of prime
importance, as they help in finding appropriate match for transplant.
Autologous stem cell transplant has become convenient mainly due to
advent of induced pluripotent stem cells (iPSC). Scientists are
trying to develop organs from human induced pluripotent stem cells
(iPSCs). An article published in Nature in 2013, reports the
generation of a functional human organ from pluripotent stem cells.
This technique surpasses the risk of immunosuppression and
graft-vs-host disease associated with bone marrow transplant.
Although expensive, the chances of success are higher in case of iPSC
transplant procedures. Currently, the market for tissue transplant
products and services is mainly driven by various advancements in
iPSC methods.
Key Market Competitors:
The key players operating in the Global Tissue Transplantation
Products and Services Market are – Abbott, Biomet, CryoLife, Inc.,
Arthrex, Exactech, Inc., Celera, Folio Biosciences, Köhler Chemie,
Bristol-Myers, LifeCell Corporation, Centacor and Novartis.
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