Advancements in molecular biology has greatly reshaped the
pharmaceutical and biotechnology industry over the last couple of
decades. Rapid innovations in healthcare technology has also boosted
growth of pharmaceuticals verticals, including alkaline proteases
market scenario.
Enzymes have long been used as alternatives to chemicals to improve
the efficiency and cost-effectiveness of a wide range of industrial
systems and processes. Alkaline proteases also known as basic
proteases are a group of enzymes used primarily as additives in
detergents and are active in a neutral to alkaline pH range. Most
alkaline proteases have an optimal pH of around 10, with an
isoelectric point of around pH 9. These are produced by alkalophilic
micro-organisms and can resist extreme alkaline environments produced
by a wide range of alkalophilic microorganisms. Alkaline proteases
are obtained from various microbial sources such as fungi, bacteria,
and certain yeasts.
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Alkaline
Proteases Market Dynamics
Alkaline protease enzymes demonstrate high stability and resistance
to proteolytic hydrolysis, owing to their high degree of
cross-linking to hydrogen bonds, disulphide bonds, and hydrophobic
interactions. They are stable in association with chelating agents
and perbonates. Developments in field of protein engineering coupled
with development of industrial enzymes is expected to create
substantial demand for industry players in artificial proteases
market.
Global
Key Players
Ab Enzymes, Acumedia Manufacturers, Inc., Advanced Enzymes,
Novozymes, Noor Enzymes, Royal DSM, Sigma Aldrich Corporation, Solvay
Enzymes and Specialty Enzymes & Biotechnologies Co. are some of
the key players in the global alkaline proteases market.
Alkaline
Proteases Market Applications
On the basis of application, the alkaline proteases market size has
been classified into detergents, pharmaceuticals, meat tenderizers,
protein hydrolyzates, food products, and waste processing. Alkaline
proteases play a crucial role in the bioprocessing of used X-ray or
photographic films for silver recovery. The use of alkaline proteases
in detergents is being increasingly preferred over conventional
synthetic ones due to their better cleaning properties, safer dirt
removal conditions, and higher performance efficiency at lower
washing temperature. Immobilized alkaline protease obtained from
Bacillus subtilis has been studied for development of ointment
compositions, non-woven tissues, gauze, and new bandage materials.
Aspergillus oryzae derived proteases are used as a diagnostic aid in
certain lytic enzyme deficiency syndrome. Alkaline proteases with
keratinolytic activity are being explored in feather degradation and
feather meal production for glues, fertilizers, biodegradable foils,
and films.
Alkaline
Proteases Market Taxonomy
The
global alkaline protease market outlook can be segmented on the basis
of:
- Type
- Source
- Application
- Geography
Serine protease and metalloprotease are the two types of alkaline
proteases. They are also classified as endo-peptidases and
exo-peptidases based on the position of the peptide bond cleavage.
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